adcetris（brentuximab vedotin）
Brentuximab vedotinis used to treat classical Hodgkin lymphoma.
Brentuximab vedotinis also used to treat anaplastic large cell lymphoma that affects organs throughout the body (systemic) or that is confined only to the skin (primary cutaneous).
Brentuximab vedotinis sometimes given after other treatments have failed.
Brentuximab Vedotin也可以用于本药物指南中未列出的目的。
警告
我应该知道的最重要的信息是什么adcetris（brentuximab vedotin）?
You should not be treated with brentuximab vedotin if you are allergic to it, or:
- 如果您还接受了另一种称为博来霉素的癌症药物。
Tell your doctor if you have ever had:
- diabetes;
- liver disease;
- 肾脏疾病;或者
- 外周血管疾病，例如Raynaud综合征。
使用这种药物的男人和女人都应使用有效的节育来防止怀孕。如果母亲或父亲正在使用这种药物，则布伦替昔单抗Vedotin可能会伤害未出生的婴儿或导致出生缺陷。
Keep using birth control for at least 6 months after your last dose of brentuximab vedotin.Tell your doctor right away if a pregnancy occurs while either the mother or the father is using brentuximab vedotin.
使用brentuximab vedotin时，您不应母乳喂养。
Side Effects
什么是副作用adcetris（brentuximab vedotin）?
如果有紧急医疗帮助signs of an allergic reaction(hives, difficult breathing, swelling in your face or throat)或严重的皮肤反应（发烧，喉咙痛，眼睛燃烧，皮肤疼痛，红色或紫色的皮疹，会散布并引起起泡和脱皮）。
Some side effects may occur during the injection or within 24 hours afterward.Tell your caregiver right awayif you feel dizzy, nauseated, chilled or feverish, or if you have itching or trouble breathing.
Brentuximab vedotinmay cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly.
Also call your doctor if you have any of these other serious side effects,even if they occur several months after you receive brentuximab vedotin:
- 麻木，虚弱，灼痛，痛苦的感觉或手臂或腿部感觉失去；
- 突然的胸痛或不适，喘息，干咳嗽，感觉不到呼吸；
- 小便时疼痛或燃烧；
- 高血糖- 口渴，排尿增加，口干，果味呼吸气味；
- 酮症酸中毒（血液中的酸太多）--nausea, vomiting, stomach pain, confusion, unusual drowsiness, or trouble breathing; or
- low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath;
- signs of tumor cell breakdown--confusion, weakness, muscle cramps, nausea, vomiting, fast or slow heart rate, decreased urination, tingling in your hands and feet or around your mouth;
- pancreatitis--severe pain in your upper stomach spreading to your back, nausea and vomiting;
- liver problems- 食欲不振，胃痛（右上侧），疲倦，黑暗尿液，黄疸（皮肤或眼睛发黄）；或者
- 胃部问题- 胃部的便秘，新的或恶化的胃痛，血腥或磨砂膏，咳嗽或呕吐，看起来像咖啡斑。
常见的副作用可能包括：
- 麻木或刺痛；
- 发烧;
- 低血细胞计数；
- nausea, vomiting, diarrhea, constipation; or
- feeling tired.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
怀孕和母乳喂养
我能拿吗adcetris（brentuximab vedotin）如果我怀孕还是母乳喂养？
使用brentuximab vedotin时，您不应母乳喂养。
互动
What drugs and food should I avoid while takingadcetris（brentuximab vedotin）?
遵循医生关于食物，饮料或活动的任何限制的指示。
Dosage Guidelines & Tips
How to takeadcetris（brentuximab vedotin）?
采用adcetris（brentuximab vedotin）exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Brentuximab vedotinis given as an infusion into a vein. A healthcare provider will give you this injection.
布伦替昔单抗vedotin通常每2到3周一次。Follow your doctor's dosing instructions very carefully.
You may be given other medications to help prevent serious side effects or an allergic reaction. Keep using these medicines for as long as your doctor has prescribed.
Brentuximab vedotincan lower your blood cell counts.Your blood will need to be tested often.Your cancer treatments may be delayed based on the results.
brentuximab vedotin剂量基于体重。如果您增加或减肥，您的剂量需求可能会改变。
如果你需要手术, tell your surgeon you currently use this medicine. You may need to stop for a short time.
Call your doctor if you miss an appointment for your brentuximab vedotin injection.