Comtan (Oral)

Drugs & Supplements

Comtan (Oral)

Generic Name: Entacapone
Reviewed:

When used with carbidopa and levodopa (Atamet, Parcopa, Sinemet), entacapone increases levels of levodopa in the body.

Entacapone is used together with carbidopa and levodopa to treat "wearing-off" symptoms of Parkinson's disease, such as stiffness, tremors, muscle spasms, and poor muscle control.

Entacapone may also be used for purposes not listed in this medication guide.

uses

What isComtan (Oral)used for?

warnings

我应该kn最重要的信息是什么呢ow aboutComtan (Oral)?

You should not use entacapone if you are allergic to it.

To make sure entacapone is safe for you, tell your doctor if you have:

  • low blood pressure;
  • liver disease; or
  • a history of mental illness or psychosis.

You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs.

People with Parkinson's disease may have a higher risk of skin cancer (melanoma). Talk to your doctor about this risk and what skin symptoms to watch for. You may need to have regular skin exams.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether entacapone passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

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Side Effects

What are the side effects ofComtan (Oral)?

Get emergency medical help if you havesigns of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • agitation, confusion, unusual thoughts or behavior;
  • hallucinations (hearing or seeing something that is not there);
  • very stiff (rigid) muscles, high fever, sweating, fast or uneven heartbeats, tremors, feeling like you might pass out;
  • severe or ongoing diarrhea;
  • restless muscle movements in your eyes, tongue, jaw, or neck (or worsening of Parkinson symptoms); or
  • unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

You may notice that your urine appears orange, red, brown, or black in color. This is not a harmful side effect unless you also have muscle pain and unusual weakness.

Common side effects may include:

  • dizziness, drowsiness;
  • nausea, vomiting, stomach pain;
  • diarrhea;
  • dry mouth; or
  • uncontrolled muscle movements.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I takeComtan (Oral)if I’m pregnant or breastfeeding?

C
Risk cannot be ruled out
Based on FDA pregnancy categories

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether entacapone passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Interactions

What drugs and food should I avoid while takingComtan (Oral)?

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.Entacapone may cause you to fall asleep suddenly, even after feeling alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid drinking alcohol. It can increase some of the side effects of entacapone.

Dosage Guidelines & Tips

How to takeComtan (Oral)?

UseComtan (Oral)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Entacapone must be taken together with carbidopa and levodopa.Entacapone used alone will not treat symptoms of Parkinson's disease.

Entacapone可以有或没有食物。塔基•ng the medicine with food may help prevent nausea, which is a common side effect of entacapone.

Drink plenty of liquids while you are taking entacapone.

Entacapone may cause you to fall asleep during normal daytime activities such as working, talking, eating, or driving. You may fall asleep suddenly, even after feeling alert. Tell your doctor if you have any problems with daytime sleepiness or drowsiness.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medicine, which can lead to severely low blood pressure or a serious electrolyte imbalance.

You should not stop using entacapone suddenly.Follow your doctor's instructions about tapering your dose.

Store at room temperature away from moisture and heat.

What should I do if I missed a dose ofComtan (Oral)?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose.Do nottake extra medicine to make up the missed dose.

Overdose Signs

What happens if I overdose onComtan (Oral)?

Overdose symptoms may include agitation and aggression, or severe drowsiness, confusion, and loss of consciousness.

If you think you or someone else may have overdosed on:Comtan (Oral), call your doctor or the Poison Control center
(800) 222-1222
If someone collapses or isn't breathing after takingComtan (Oral), call 911
911

Images

COMTAN

Color: orange

Shape: oval

Imprint: COMTAN

EN1 200

Color: brown

Shape: oval

Imprint: EN1 200

W781

Color: orange

Shape: oval

Imprint: W781

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Medical Disclaimer

Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health.
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