Idarucizumab (Intravenous)
Idarucizumab is a drug that reverses the effects of another medicine called dabigatran (Pradaxa). Dabigatran is used to prevent blood clots and strokes in people with certain heart disorders. Because the medicine keeps the blood from clotting, people taking dabigatran can bleed more easily.
在医疗紧急情况下使用idarucizumab来治疗因服用dabigatran引起的严重或不受控制的出血。
Idarucizumab is also used when an emergency surgery or other invasive medical procedure is needed in a person who takes dabigatran.
Idarucizumab may also be used for purposes not listed in this medication guide.
用途
What isIdarucizumab (Intravenous)used for?
- Reversal of Anticoagulation
警告
What is the most important information I should know aboutIdarucizumab (Intravenous)?
If possible before you receive idarucizumab, tell your doctor if you have hereditary fructose intolerance.Idarucizumab contains sorbitol (a sugar alcohol). Sorbitol can cause serious or life-threatening metabolic problems in people with hereditary fructose intolerance.
In an emergency, you may not be able to tell caregivers if you are pregnant or breast feeding. Make sure any doctor caring for your pregnancy or your baby knows you received this medicine.
Side Effects
What are the side effects ofIdarucizumab (Intravenous)?
如果有紧急医疗帮助过敏反应的迹象：hives, itching; difficult breathing; swelling of your face, lips, tongue, or throat.
当dabigatran的影响逆转时，您将不会受到保护。因此，您可能容易受到潜在疾病的影响。Until you start taking dabigatran again, watch for signs and symptoms of blood clots, such as:
- sudden numbness or weakness (especially on one side of the body);
- problems with vision or speech;
- 胸痛，喘息，咳嗽；或者
- 一条或两条腿的疼痛，肿胀，温暖或发红。
After you receive idarucizumab, tell your caregivers right away if you have any bleeding that will not stop.
Common side effects may include:
- confusion, headache;
- fever; or
- constipation.
这不是一个侧eff的完整列表ects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeIdarucizumab (Intravenous)if I’m pregnant or breastfeeding?
In an emergency, you may not be able to tell caregivers if you are pregnant or breast feeding. Make sure any doctor caring for your pregnancy or your baby knows you received this medicine.
互动
What drugs and food should I avoid while takingIdarucizumab (Intravenous)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to takeIdarucizumab (Intravenous)?
UseIdarucizumab (Intravenous)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Idarucizumab is given as an infusion into a vein. A healthcare provider will give you this injection.
After you receive idarucizumab, you may need follow-up blood tests to help your doctor determine how quickly your blood is clotting.
Once your condition is stable, you may need to restart dabigatran to prevent blood clots.Carefully follow your doctor's instructions about how soon to start taking your medicine(s) again.
Because you will receive idarucizumab in a clinical setting, you are not likely to miss a dose.
Overdose Signs
What happens if I overdose onIdarucizumab (Intravenous)?
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.