Octreotide (Sandostatin)

Octreotide is a man-made protein that is similar to a hormone in the body called somatostatin. Octreotide lowers many substances in the body such as insulin and glucagon (involved in regulating blood sugar), growth hormone, and chemicals that affect digestion.

Octreotide is used to treat acromegaly. Octreotide is also used to reduce flushing episodes and watery diarrhea caused by cancerous tumors (carcinoid syndrome) or tumors called vasoactive intestinal peptide tumors (VIPomas).

Octreotide may also be used for purposes not listed in this medication guide.

uses

What isOctreotide (Sandostatin)used for?

  • Acromegaly
  • Carcinoid Tumor
  • Vasoactive Intestinal Peptide Tumor

warnings

What is the most important information I should know aboutOctreotide (Sandostatin)?

You should not use octreotide if you are allergic to it.

Tell your doctor if you have ever had:

  • diabetes;
  • gallbladder disease;
  • heart disease, high blood pressure, or heart rhythm disorder;
  • thyroid problems;
  • pancreatitis;
  • liver disease; or
  • kidney disease (or if you are on dialysis).

Tell your doctor if you are pregnant or breastfeeding.

Using octreotide can affect certain hormones that may make it easier for you to get pregnant, even if you were unable to get pregnant before. Talk to your doctor about using birth control to avoid unwanted pregnancy.

Octreotide is not approved for use by anyone younger than 18 years old.

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Side Effects

What are the side effects ofOctreotide (Sandostatin)?

Get emergency medical help if you havesigns of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

在onc打电话给你的医生e if you have:

  • severe constipation;
  • slow or uneven heartbeats;
  • signs of gallstones--fever, chills, nausea, vomiting, severe pain in your upper stomach spreading to your back, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor;
  • 低血糖--headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky; or
  • underactive thyroid--extreme tired feeling, dry skin, joint pain or stiffness, muscle pain or weakness, hoarse voice, feeling more sensitive to cold temperatures, weight gain.

Common side effects may include:

  • gallstones;
  • nausea, vomiting, diarrhea, stomach pain, gas;
  • headache, back pain; or
  • dizziness, tiredness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I takeOctreotide (Sandostatin)if I’m pregnant or breastfeeding?

B
No evidence of risk in humans
Based on FDA pregnancy categories

Tell your doctor if you are pregnant or breastfeeding.

Using octreotide can affect certain hormones that may make it easier for you to get pregnant, even if you were unable to get pregnant before. Talk to your doctor about using birth control to avoid unwanted pregnancy.

Interactions

What drugs and food should I avoid while takingOctreotide (Sandostatin)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Dosage Guidelines & Tips

How to takeOctreotide (Sandostatin)?

UseOctreotide (Sandostatin)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Octreotideoralis taken by mouth.

Octreotideinjectionis injected under the skin, into a muscle, or as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.

Read and carefully follow any Instructions for Use provided with your medicine.Ask your doctor or pharmacist if you don't understand all instructions.

Swallow thecapsulewhole and do not crush, chew, break, or open it.

Take thecapsulewith a full glass of water on an empty stomach, at least 1 hour before or 2 hours after a meal.

You may need to mix octreotideinjectionwith a liquid (diluent) before using it. When using injections by yourself, be sure you understand how to properly mix and store the medicine.

Be sure to follow the instructions for the exact type of octreotide your doctor has prescribed for you.

准备注射只有当你准备give it.Do not use if the medicine has changed colors or has particles in it.Call your pharmacist for new medicine.

Your healthcare provider will show you where on your body to inject octreotide. Use a different place each time you give an injection. Do not inject into the same place two times in a row.

You will need frequent medical tests.

If you need radiation treatment, you may need to stop using this medicine for a short time.Follow your doctor's instructions very carefully.

Store unopened octreotide in the original carton in the refrigerator. Protect from light. Do not freeze.

Once you have started taking octreotidecapsulesstore them at room temperature away from moisture and heat. Keep each capsule in the blister pack until you are ready to take the medicine.

Take theampulout of the refrigerator and let it reach room temperature before injecting your dose.Do not heat the ampul.Each ampul is for one use only. Throw it away after one use, even if there is still medicine left inside.

You may also store an unopenedampulat room temperature for up to 14 days. Throw away the ampul if not used within 14 days.

Once you begin using yourinjection pen, you may store it at room temperature for up to 28 days. Do not freeze, and throw the pen away if it has been frozen.

Throw theinjection penaway 28 days after your first use, even if there is still medicine left inside.

Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.

What should I do if I missed a dose ofOctreotide (Sandostatin)?

Call your doctor for instructions if you miss a dose.

Overdose Signs

What happens if I overdose onOctreotide (Sandostatin)?

Overdose symptoms may include severe upper stomach pain, diarrhea, weight loss, warmth or tingling, numbness or cold feeling, unexplained muscle pain, weakness, weak pulse, fainting, or slow breathing (breathing may stop).

If you think you or someone else may have overdosed on:Octreotide (Sandostatin), call your doctor or the Poison Control center
(800) 222-1222
If someone collapses or isn't breathing after takingOctreotide (Sandostatin),拨打911
911

Images

No image available

OT, 20

Color: white

Shape: capsule

Imprint: OT, 20

Medical Disclaimer

Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health.
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