Ofatumumab（Arzerra）
该传单提供有关Ofatumumab两个不同品牌的信息。
Arzerrais used to treat chronic lymphocytic leukemia (CLL), sometimes in combination with other cancer medicines.
凯西普塔is used to treat relapsing forms of multiple sclerosis in adults (including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease).
Ofatumumab may also be used for purposes not listed in this medication guide.
warnings
什么是the most important information I should know aboutOfatumumab（Arzerra）？
你不应该使用凯西普塔if you have active hepatitis B.
Tell your doctor if you have ever had:
- 活跃或慢性感染；
- a condition for which you have used an immunosuppressant medication; or
- hepatitis B.
You may need to take antiviral medicine if you are found to have any risk factors for hepatitis B. Follow your doctor's dosing instructions very carefully.
在开始使用Ofatumumab之前，您应该是所有疫苗的最新信息。Tell your doctor if you have received any vaccines within the past 4 weeks.
告诉医生您是否怀孕或打算怀孕。
Kesimpta可能会伤害未出生的婴儿。使用有效的节育措施在使用时防止怀孕凯西普塔，，，，and for at least 6 months after your last dose.
如果您在怀孕时使用手atumumab，请确保任何照顾新婴儿的医生都知道您在怀孕期间使用了药物。在子宫中暴露于Ofatumumab可能会影响婴儿在生命的前6个月内的疫苗接种时间表。
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
副作用
What are the side effects ofOfatumumab（Arzerra）？
Get emergency medical help if you have过敏反应的迹象：hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection or up to 24 hours later.Tell your caregiver right away if you feel dizzy, tired, nauseated, light-headed, feverish, chilled, sweaty, itchy, or have a skin rash, headache, muscle pain, back pain, stomach pain, irregular heartbeats, chest tightness, trouble breathing, or swelling and irritation in your throat.
Ofatumumab may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly.
如果有的话，请立即致电医生：
- 注射药物的疼痛，发红，肿胀或瘙痒；
- right-sided upper stomach pain, vomiting, loss of appetite, yellowing of your skin or eyes, and not feeling well;
- 肺部感染- 狂热，发冷，咳嗽，粘液，胸痛，感到呼吸不足；
- 低血细胞计数- 狂热，寒冷，疲倦，嘴巴疮，皮肤疮，易于瘀伤，不寻常的出血，皮肤苍白，手和脚，感觉浅或呼吸不足；或者
- 肿瘤细胞分解的迹象- 培养，无力，肌肉痉挛，恶心，呕吐，腹泻，快速或缓慢的心率，手和脚或嘴巴周围的刺痛。
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common side effects may include:
- side effects during an infusion;
- 注射注射的刺激；
- 发烧，血细胞计数低；
- cold symptoms such as stuffy nose, sneezing, sore throat;
- 咳嗽，胸部紧绷，呼吸困难，肺部感染；
- 腹泻，恶心；
- rash; or
- headache, tiredness.
这不是副作用的完整列表，其他可能发生。打电话给您的医生，征求有关副作用的医疗建议。您可以致电1-800-FDA-1088向FDA报告副作用。
Pregnancy & Breastfeeding
Can I takeOfatumumab（Arzerra）if I’m pregnant or breastfeeding?
告诉医生您是否怀孕或打算怀孕。
Kesimpta可能会伤害未出生的婴儿。使用有效的节育措施在使用时防止怀孕凯西普塔，，，，and for at least 6 months after your last dose.
如果您在怀孕时使用手atumumab，请确保任何照顾新婴儿的医生都知道您在怀孕期间使用了药物。在子宫中暴露于Ofatumumab可能会影响婴儿在生命的前6个月内的疫苗接种时间表。
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
Interactions
我应该避免使用什么药物和食物Ofatumumab（Arzerra）？
You should not receive a vaccine while using ofatumumab.某些疫苗可能无法正常工作，也可能无法完全保护您免受疾病的侵害。在使用Ofatumumab时，其他疫苗可能对您不安全。疫苗包括预防流感，麻疹，腮腺炎，红宝石（MMR），轮状病毒，伤寒，黄热病，水痘（水痘）和疱疹带状疱疹（带状疱疹）（带状疱疹）的疫苗。
剂量指南和提示
如何服用Ofatumumab（Arzerra）？
UseOfatumumab（Arzerra）exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using ofatumumab.
Arzerrais given as an infusion into a vein. A healthcare provider will give you this injection. You may be given other medications to help prevent a reaction to the infusion. You may need to start using these medications up to 2 hours before the start of your ofatumumab infusion.
Arzerra通常在28天的治疗周期中给出。您可能只需要在每个周期的前1或2周内使用药物。您的给药时间表可能会进一步改变。您的医生将确定用Ofatumumab治疗多长时间。
Arzerramust be given slowly, and one infusion can take up to several hours to complete.
凯西普塔通常每月一次注射皮肤下。前3剂每周给予。医疗保健提供者可以教您如何自己正确使用药物。
阅读并仔细遵循医学中提供的任何说明。Ask your doctor or pharmacist if you don't understand all instructions.
仅在准备好给它时准备注射。Do not use if the medicine looks cloudy, has changed colors, or has particles in it.致电您的药剂师新药。
Avoid injecting凯西普塔进入疤痕，痣或妊娠纹，或进入红色，瘀伤，鳞片，硬或嫩的皮肤。
使用Ofatumumab时，您将需要经常进行医学测试，并且您的下一个剂量可能会根据结果延迟。
If you've ever had hepatitis B, using ofatumumab can cause this virus to become active or get worse.停止后几个月，您可能需要经常进行肝功能测试。
店铺凯西普塔prefilled syringes in their original carton in a refrigerator. Protect from light and freezing. Do not shake the syringe.
每个凯西普塔预填充注射器仅用于一种用途。一次用途后将其扔掉，即使里面仍然剩下药物。
仅使用针和注射器一次，然后将它们放入防线“锋利”容器中。遵循有关如何处置该容器的州或地方法律。将其远离儿童和宠物的范围。
Call your doctor for instructions if:
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如果您错过了每月剂量的凯西普塔，，，，use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.Do not一次使用两剂。