Oliceridine (Intravenous)
Oliceridine is an opioid medicine that is used to treat severe pain when other treatments have not provided relief.
Oliceridine may also be used for purposes not listed in this medication guide.
uses
What isOliceridine (Intravenous)used for?
- Pain
warnings
What is the most important information I should know aboutOliceridine (Intravenous)?
You should not use oliceridine if you are allergic to it, or if you have:
- severe asthma or breathing problems; or
- a stomach or bowel obstruction (including paralytic ileus).
In some people, oliceridine breaks down very slowly in the liver and reaches higher than normal levels in the body. This can cause dangerously slow breathing and may cause death. Tell your doctor if you've ever been told you are a "poor metabolizer."
Tell your doctor if you have ever had:
- asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder;
- liver disease;
- low blood pressure;
- long QT syndrome (in you or a family member);
- drug or alcohol addiction;
- depression, mental illness;
- problems with your gallbladder or pancreas; or
- a head injury, brain tumor, or seizure.
If you use opioid medicine while you are pregnant, your baby could become dependent on the drug.This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on opioids may need medical treatment for several weeks.
Long-term use of opioid medication may affect fertility (ability to have children)in men or women.It is not known whether opioid effects on fertility are permanent.
Ask a doctor before using this medicine if you are breastfeeding.Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.
Side Effects
What are the side effects ofOliceridine (Intravenous)?
Get emergency medical help if you havesigns of an allergic reaction:hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Opioid medicine can slow or stop your breathing, and death may occur.A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.
马上打电话给你的医生如果你有:
- noisy breathing, sighing, shallow breathing, breathing that stops during sleep;
- a slow heart rate or weak pulse;
- a light-headed feeling, like you might pass out;
- severe constipation;
- low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet;
- low cortisol levels--nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness; or
- low oxygen in your blood--confusion, feeling restless or short of breath, blue-colored lips or skin.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as:agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
Serious breathing problems may be more likely in older adults and in those who are debilitated or have wasting syndrome or chronic breathing disorders.
Common side effects may include:
- nausea, vomiting, constipation;
- headache, dizziness;
- itching; or
- low oxygen in your blood.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeOliceridine (Intravenous)if I’m pregnant or breastfeeding?
If you use opioid medicine while you are pregnant, your baby could become dependent on the drug.This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on opioids may need medical treatment for several weeks.
Ask a doctor before using this medicine if you are breastfeeding.Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.
Interactions
What drugs and food should I avoid while takingOliceridine (Intravenous)?
Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.
Dosage Guidelines & Tips
How to takeOliceridine (Intravenous)?
UseOliceridine (Intravenous)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Oliceridine is given around the clock (continuous) using an infusion pump attached to a catheter placed into a vein. A healthcare provider can teach you how to properly use the infusion pump by yourself.
Never use oliceridine in larger amounts, or for longer than prescribed.Tell your doctor if you feel an increased urge to use more of this medicine.
Never share opioid medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH.保持药物在其他地方不能get to it. Selling or giving away opioid medicine is against the law.
Tell your caregivers if you feel any burning, pain, or swelling around your port needle.
If you have used opioid medicine regularly and are opioid-dependent, you should not stop using oliceridine suddenly,or you could have unpleasant withdrawal symptoms. Follow your doctor's instructions about tapering your dose.
Since oliceridine is used for pain, you are not likely to miss a dose. The infusion pump will control how much and how often you use this medicine.
Overdose Signs
What happens if I overdose onOliceridine (Intravenous)?
Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.
Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.