Drospirenone is a female hormone that helps regulate ovulation and menstruation.
Estradiol is a female hormone involved in development and maintenance of the female reproductive system.
Drospirenone and estradiol is a combination medicine used to treat symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation. This medicine is for use only if you have a uterus (if you have not had a hysterectomy).
Drospirenone and estradiol may also be used for purposes not listed in this medication guide.
uses
What isAngeliq (Oral)used for?
- Postmenopausal Symptoms
warnings
What is the most important information I should know aboutAngeliq (Oral)?
You should not use this medicine if you are allergic to drospirenone or estradiol, or if you have:
- unusual vaginal bleeding that a doctor has not checked;
- a bleeding disorder;
- coronary artery disease;
- a history of heart attack, stroke, or blood clot;
- kidney disease;
- liver disease;
- an adrenal gland disorder;
- a history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina; or
- if you have had your uterus removed (hysterectomy).
Do not use drospirenone and estradiol if you are pregnant.Tell your doctor right away if you become pregnant during treatment.
Taking this medicine can increase your risk of blood clots, stroke, or heart attack.You are even more at risk if you have high blood pressure, diabetes, high cholesterol, if you are overweight, or if you smoke.
Drospirenone and estradiol should not be used to prevent heart disease, stroke, or dementia, because this medicine may actually increase your risk of developing these conditions.
Tell your doctor if you have ever had:
- heart disease, high blood pressure;
- a thyroid disorder;
- gallbladder disease;
- jaundice caused by pregnancy or taking hormones;
- high triglycerides (a type of fat in the blood);
- asthma;
- epilepsy or other seizure disorder;
- migraine headaches;
- lupus;
- endometriosis or uterine fibroid tumors;
- high levels of calcium or potassium in your blood, or low sodium levels;
- hereditary angioedema (an immune system disorder); or
- porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).
Using drospirenone and estradiol may increase your risk of breast cancer. Talk with your doctor about your risk before using this medicine long term.
This medicine lowers the hormone needed to produce breast milk and can slow breast milk production. You should not breast-feed while taking drospirenone and estradiol.
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Overall rating forAngeliq (Oral)
Side Effects
What are the side effects ofAngeliq (Oral)?
Get emergency medical help if you havesigns of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
马上打电话给你的医生如果你有:
- heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
- signs of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;
- signs of a blood clot--sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, pain or warmth in one or both legs;
- sudden vision loss;
- swelling, rapid weight gain;
- jaundice (yellowing of the skin or eyes);
- memory problems, confusion, unusual behavior;
- unusual vaginal bleeding;
- a lump in your breast; or
- high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor.
Common side effects may include:
- headache, mood changes;
- vaginal itching or discharge, changes in your menstrual periods, breakthrough bleeding;
- breast pain;
- nausea, diarrhea, stomach pain; or
- fluid retention (swelling, rapid weight gain).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeAngeliq (Oral)if I’m pregnant or breastfeeding?
Do not use drospirenone and estradiol if you are pregnant.Tell your doctor right away if you become pregnant during treatment.
This medicine lowers the hormone needed to produce breast milk and can slow breast milk production. You should not breast-feed while taking drospirenone and estradiol.
Interactions
What drugs and food should I avoid while takingAngeliq (Oral)?
Avoid smoking. It can greatly increase your risk of blood clots, stroke, or heart attack while using this medicine.
Grapefruit may interact with drospirenone and estradiol and lead to unwanted side effects.Avoid the use of grapefruit products.
Dosage Guidelines & Tips
How to takeAngeliq (Oral)?
UseAngeliq (Oral)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Do not crush, chew, break, or dissolve a drospirenone and estradiol tablet. Swallow it whole.
Take this medicine at the same time each day.
Drospirenone and estradiol may increase your risk of developing a condition that may lead to uterine cancer. Your doctor may prescribe a progestin to help lower this risk.Report any unusual vaginal bleeding right away.
If you need major surgery or will be on long-term bed rest,you may need to stop using this medicine for a short time. Any doctor or surgeon who treats you should know that you are using drospirenone and estradiol.
Your doctor should check your progress on a regular basis to determine whether you should continue this treatment. Self-examine your breasts for lumps on a monthly basis, and have regular mammograms while using this medicine.
Store at room temperature away from moisture and heat.
Take the medicine as soon as you can, but skip the missed dose if you are more than 12 hours late for the dose.Do nottake two doses at one time.
Overdose Signs
What happens if I overdose onAngeliq (Oral)?
Images
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Color: pink
形状: round
Form: film coated
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