阿托品和解磷定(Duodote)
一个tropine and pralidoxime is a combination medicine used as an antidote to treat poisoning by a pesticide (insect spray) or a chemical that interferes with the central nervous system, such as nerve gas.
This medicine is not effective as an antidote for all types of pesticide poisonings. You may need medications or additional treatments.
一个tropine and pralidoxime may also be used for purposes not listed in this medication guide.
uses
What is阿托品和解磷定(Duodote)used for?
- Organophosphate Poisoning
- Nerve Agent Poisoning
warnings
What is the most important information I should know about阿托品和解磷定(Duodote)?
If possible, before you receive atropine and pralidoxime, tell your doctor if you have ever had:
- an allergy to any medication;
- heart problems, a heart attack or stroke;
- high blood pressure;
- liver or kidney disease;
- asthma, COPD (chronic obstructive pulmonary disorder), or other breathing problem;
- glaucoma; or
- urination problems.
In an emergency situation it may not be possible to tell your caregivers if you are pregnant or breast-feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received this medicine.
Side Effects
What are the side effects of阿托品和解磷定(Duodote)?
Get emergency medical help if you havesigns of an allergic reaction:hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Some of the side effects of atropine and pralidoxime may be similar to the symptoms of poisoning.Your caregivers will watch you closely to determine whether your body is responding well to the medication, or if you are having any serious side effects.
Tell your caregivers right away if you have:
- pounding heartbeats or fluttering in your chest;
- chest pain spreading to your jaw or shoulder;
- trouble swallowing;
- painful or difficult urination;
- little or no urination;
- unusual changes in mood or behavior; or
- blurred vision, tunnel vision, eye pain, or seeing halos around lights.
Side effects may be more likely in older adults.
Common side effects may include:
- trouble breathing;
- dry mouth;
- dry eyes, vision changes, increased sensitivity to light;
- nausea, vomiting;
- 快速的心跳, increased blood pressure;
- behavior changes, feeling excited or confused;
- decreased urination;
- headache, dizziness, drowsiness;
- muscle weakness;
- dry skin, rash; or
- abnormal liver function tests.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take阿托品和解磷定(Duodote)if I’m pregnant or breastfeeding?
In an emergency situation it may not be possible to tell your caregivers if you are pregnant or breast-feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received this medicine.
Interactions
What drugs and food should I avoid while taking阿托品和解磷定(Duodote)?
一个void becoming overheated or dehydrated during exercise and in hot weather. Atropine can decrease sweating and you may be more prone to heat stroke for a short time after receiving this medication.
Dosage Guidelines & Tips
How to take阿托品和解磷定(Duodote)?
Use阿托品和解磷定(Duodote)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
一个tropine and pralidoxime is injected into a muscle in your upper thigh. A healthcare provider will give you this injection.
一个tropine and pralidoxime is usually given as soon as possible after the onset of poisoning symptoms. If you still have symptoms after 10 to 15 minutes, you will receive 2 more injections.
Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely.
You may be watched for up to 72 hours to make sure the medicine has been effective and you no longer have any effects of the poison.
Since atropine and pralidoxime is used when needed, it does not have a daily dosing schedule.
Overdose Signs
What happens if I overdose on阿托品和解磷定(Duodote)?
Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.