Cabenuva 400/600（肌内）
Cabotegravir和Rilpivirineare antiviral medicines that prevent human immunodeficiency virus (HIV) from multiplying in your body. HIV is the virus that can cause acquired immunodeficiency syndrome (AIDS).
Cabotegravir和Rilpivirineis a combination medicine that is used without any other antiviral medicines to treat HIV.这种药物不能治愈艾滋病毒或艾滋病。
Cabotegravir和Rilpivirineis for use in adults who have already used other antiviral HIV medications that have controlled their viral load.
Cabotegravir和Rilpivirine也可以用于本药物指南中未列出的目的。
uses
什么是Cabenuva 400/600（肌内）used for?
- 艾滋病毒感染
warnings
什么是the most important information I should know aboutCabenuva 400/600（肌内）？
You should not use cabotegravir and rilpivirine if you are allergic to it.
许多药物可以相互作用并引起危险的影响。某些药物不应与Cabotegravir和Rilpivirine一起使用。Your doctor may change your treatment plan if you also use:
- 地塞米松（超过1剂）；
- methadone;
- St. John's wort;
- certain antibiotics- 亚霉素，克拉霉素，红霉素，利福丁，利福平，利福平；或者
- 癫痫病--carbamazepine, oxcarbazepine, phenobarbital, phenytoin.
Cabotegravir和Rilpivirinecan stay in your system for 12 months or longer. If you stop using cabotegravir and rilpivirine, follow your doctor's instructions about using any other medicines during the first year afterward.
告诉你的医生如果你有过:
- 服用含有cabotegravir或rilpivirine的药物后，皮疹或过敏反应；
- 肝病，包括丙型肝炎或C（Cabotegravir和Rilpivirine可能会影响您的肝功能测试的结果）；
- 精神疾病;或者
- 长QT综合征（在您或家庭成员中）。
Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby. However, HIV can be passed to your baby if the virus is not controlled during pregnancy. Your name may be listed on a registry to track any effects of cabotegravir and rilpivirine on the baby.
Women with HIV or AIDS should not breastfeed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.
副作用
What are the side effects ofCabenuva 400/600（肌内）？
Get emergency medical help if you have过敏反应的迹象：hives; fever, tiredness, body aches, not feeling well; sores or blisters in your mouth; red or puffy eyes; difficult breathing; swelling of your face, lips, tongue, or throat.
如果您患有严重的药物反应，可能会影响身体的许多部位，请寻求医疗治疗。症状可能包括：皮疹，发烧，腺体肿胀，肌肉酸痛，严重的无力，不寻常的瘀伤或皮肤或眼睛发黄。
Your cabotegravir and rilpivirine injections may be permanently discontinued if you have an allergic reaction.
注射后几分钟内可能会发生一些副作用。告诉您的护理人员，您是否感到焦虑，温暖，头脑疲倦，出汗，胃痛或麻木。
如果有的话，请立即致电医生：
- 情绪或行为的异常变化；
- suicidal thoughts or actions; or
- 肝脏问题- 食欲，恶心，呕吐，胃痛（右上侧），瘙痒，深色尿液，粘土色的凳子，黄疸（皮肤或眼睛的黄色）。
Common side effects may include:
- 疼痛，发红，肿胀，瘙痒，瘀伤，温暖或在注射的地方硬肿块；
- fever;
- 恶心;
- 骨头，关节或肌肉疼痛；
- 感到疲倦，睡眠问题；
- headache, dizziness; or
- rash.
这不是副作用的完整列表，其他可能发生。打电话给您的医生，征求有关副作用的医疗建议。您可以致电1-800-FDA-1088向FDA报告副作用。
Pregnancy & Breastfeeding
Can I takeCabenuva 400/600（肌内）if I’m pregnant or breastfeeding?
Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby. However, HIV can be passed to your baby if the virus is not controlled during pregnancy. Your name may be listed on a registry to track any effects of cabotegravir and rilpivirine on the baby.
Women with HIV or AIDS should not breastfeed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.
Interactions
我应该避免使用什么药物和食物Cabenuva 400/600（肌内）？
Cabotegravir和Rilpivirine是HIV的完整治疗方法。除非您的医生告诉您，否则请勿使用其他HIV药物。
Using this medicine may not prevent your disease from spreading.Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.
剂量指南和提示
如何服用Cabenuva 400/600（肌内）？
UseCabenuva 400/600（肌内）完全按照标签或医生的规定。不要在较大或较小的量或更长的时间内使用。
第一次注射之前至少28天，您将每天用餐一次服用Cabotegravir和Rilpivirine，每天用餐一次。这种“铅剂量”将有助于确定您可以安全地一起使用这些药物。按照您的处方标签上的所有指示，并完全按照指示使用这些药物。
在您服用平板电脑的最后一天，you will receive your first injectable dose of this medicine. Cabotegravir and rilpivirine is injected into a muscle once per month. A healthcare provider will give you this medicine as 2 separate injections in opposite sides of your buttocks.
One month after your first injectable dose,you will begin regular monthly cabotegravir and rilpivirine injections. You will be watched closely for about 10 minutes after each injection, to make sure you do not have a serious reaction.
您的每月注射时间对艾滋病毒治疗的成功非常重要。Your doctor may set a calendar day as your "target treatment date" to help keep you on schedule. If needed, you may receive an injection early or late, up to 7 days before or 7 days after your target date.
You must remain under the care of a doctor while receiving cabotegravir and rilpivirine injections. Stay on schedule to get the most benefit.Missing doses can increase your risk of HIV that is resistant to medication.
If you stop using cabotegravir and rilpivirine, you will need to start using other HIV medicines within 1 month to prevent your condition from becoming resistant.
You will need frequent medical tests. Cabotegravir and rilpivirine can have long lasting effects on your body (up to 12 months after your last dose). You may still need medical tests for a short time after you stop using this medicine.
如果您错过了Cabotegravir和Rilpivirine注射的约会，请致电医生以获取指示。
If you plan to miss an injection by more than 7 days,您可能需要每天服用Cabotegravir和Rilpivirine片剂，直到下一次每月注射为止。您应该在上次注射后大约1个月开始服用平板电脑。如果需要，每日平板电脑可以连续2个月更换Cabotegravir和Rilpivirine注射。
如果您错过了7天的注射，并且还没有开始以平板电脑的形式服用药物，那么您的医生可能需要确定Cabotegravir和Rilpivirine是否是您的最佳治疗方法。