Coagulation Factor Xa (Intravenous)

Coagulation Factor Xa (Intravenous)

Brand Names: Andexxa

Coagulation factor Xa is a protein that reverses the effects of certain anticoagulant medications that are used to treat or prevent blood clots. Reversing anticoagulant medicine is necessary if you have uncontrolled or life-threatening bleeding as a result of how that medicine works.

凝血因子XA用于治疗抗凝剂Rivaroxaban(Xarelto)和Apixaban(Eliquis)的人中的不受控制的出血。

Coagulation factor Xa was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, healthy volunteers responded to this medicine, but further studies are needed.

Coagulation factor Xa may also be used for purposes not listed in this medication guide.

用途

What isCoagulation Factor Xa (Intravenous)used for?

  • Reversal of Anticoagulation

警告

What is the most important information I should know aboutCoagulation Factor Xa (Intravenous)?

如果您对凝血因子药物有过敏反应,则不应接受凝血因子XA的治疗。

In an emergency, you may not be able to tell caregivers about your health conditions. Make sure any doctor caring for you afterward knows you received this medicine.

In an emergency, you may not be able to tell caregivers if you are pregnant or breast feeding. Make sure any doctor caring for your pregnancy or your baby knows you received this medicine.

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Side Effects

What are the side effects ofCoagulation Factor Xa (Intravenous)?

如果有紧急医疗帮助signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

马上打电话给你的医生如果你有:

  • pain or burning when you urinate;
  • 咳嗽,粘液,胸痛和呼吸急促;
  • 发烧,发冷;或者
  • continued bleeding after treatment.

逆转抗凝药物的影响可能会增加您患血块,心脏病发作,中风或死亡的风险。如果您在接受凝结因子XA治疗后患有任何这些症状,请获得紧急医疗帮助,尤其是如果您尚未开始再次服用抗凝药物:

  • signs of a blood clot--sudden numbness or weakness, problems with vision or speech, swelling or redness in an arm or leg; or
  • heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating.

Common side effects of coagulation factor Xa may include:

  • lung problems;
  • painful urination; or
  • 静脉针头周围的疼痛,肿胀,燃烧或刺激。

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I takeCoagulation Factor Xa (Intravenous)if I’m pregnant or breastfeeding?

In an emergency, you may not be able to tell caregivers if you are pregnant or breast feeding. Make sure any doctor caring for your pregnancy or your baby knows you received this medicine.

互动

What drugs and food should I avoid while takingCoagulation Factor Xa (Intravenous)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Dosage Guidelines & Tips

How to takeCoagulation Factor Xa (Intravenous)?

UseCoagulation Factor Xa (Intravenous)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Coagulation factor Xa is given as an infusion into a vein. A healthcare provider will give you this injection.

This medicine must be given slowly, and the infusion can take at least 2 hours to complete.

Once your bleeding has been controlled, you may need to begin using anticoagulant medication again to prevent future blood clots.Follow your doctor's instructions very carefully.

What should I do if I missed a dose ofCoagulation Factor Xa (Intravenous)?

Because you will receive coagulation factor Xa in a clinical setting, you are not likely to miss a dose.

Overdose Signs

What happens if I overdose onCoagulation Factor Xa (Intravenous)?

如果您认为您或其他人可能过量服用:Coagulation Factor Xa (Intravenous), call your doctor or the Poison Control center
(800)222-1222
If someone collapses or isn't breathing after takingCoagulation Factor Xa (Intravenous),拨打911
911

Medical Disclaimer

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