Cyclobenzaprine (Flexeril)

Cyclobenzaprine is a medicine that’s used along with rest, physical therapy, and other measures to treat pain caused by:

  • Strains
  • Sprains
  • Other injuries

Cyclobenzaprine is a muscle relaxant. It works by blocking pain sensations that are sent to your brain.

The U.S. Food and Drug Administration (FDA) first approved this medicine in 1977.

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uses

What isCyclobenzaprine (Flexeril)used for?

  • Muscle Spasm
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warnings

What is the most important information I should know aboutCyclobenzaprine (Flexeril)?

You should not use cyclobenzaprine if you are allergic to it, or if you have:

  • a thyroid disorder;
  • heart block, heart rhythm disorder, congestive heart failure; or
  • if you have recently had a heart attack.

Cyclobenzaprine is not approved for use by anyone younger than 15 years old.

Do not use cyclobenzaprine if you have taken an MAO inhibitor in the past 14 days.A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Some medicines can interact with cyclobenzaprine and cause a serious condition calledserotonin syndrome.Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting.Ask your doctor before making any changes in how or when you take your medications.

Tell your doctor if you have ever had:

  • liver disease;
  • glaucoma;
  • enlarged prostate; or
  • problems with urination.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

Older adults may be more sensitive to the effects of this medicine.

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User Reviews & Rating

Overall rating forCyclobenzaprine (Flexeril)

3.2
out of 5
Side Effects
3.0
Easy to Use
4.2
Effectiveness
3.1
Read Reviews
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Side Effects

What are the side effects ofCyclobenzaprine (Flexeril)?

Get emergency medical help if you havesigns of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using cyclobenzaprine and call your doctor at once if you have:

  • fast or irregular heartbeats;
  • chest pain or pressure, pain spreading to your jaw or shoulder; or
  • sudden numbness or weakness (especially on one side of the body), slurred speech, balance problems.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as:agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Serious side effects may be more likely in older adults.

Common side effects may include:

  • drowsiness, tiredness;
  • headache, dizziness;
  • dry mouth; or
  • upset stomach, nausea, constipation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Pregnancy & Breastfeeding

Can I takeCyclobenzaprine (Flexeril)if I’m pregnant or breastfeeding?

B
No evidence of risk in humans
Based on FDA pregnancy categories

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

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Interactions

What drugs and food should I avoid while takingCyclobenzaprine (Flexeril)?

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Avoid drinking alcohol.Dangerous side effects could occur.

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Dosage Guidelines & Tips

How to takeCyclobenzaprine (Flexeril)?

UseCyclobenzaprine (Flexeril)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Cyclobenzaprine is usually taken once daily for only 2 or 3 weeks.Follow your doctor's dosing instructions very carefully.

Swallow thecapsulewhole and do not crush, chew, break, or open it.

Take the medicine at the same time each day.

Call your doctor if your symptoms do not improve after 3 weeks, or if they get worse.

Store at room temperature away from moisture, heat, and light.

What should I do if I missed a dose ofCyclobenzaprine (Flexeril)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.Do nottake two doses at one time.

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Overdose Signs

What happens if I overdose onCyclobenzaprine (Flexeril)?

Overdose symptoms may include severe drowsiness, vomiting, fast heartbeats, tremors, agitation, or hallucinations.

If you think you or someone else may have overdosed on:Cyclobenzaprine (Flexeril), call your doctor or the Poison Control center
(800) 222-1222
If someone collapses or isn't breathing after takingCyclobenzaprine (Flexeril),拨打911
911
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What to Expect

你可能会开始感到有些节律的影响lobenzaprine within 20 to 30 minutes of taking it. The peak concentration varies, depending on what formulation you take. For example, the peak concentration for the extended-release pills is around seven hours.

The immediate-release tablets last for about four to six hours, while the extended-release tablets last around 24 hours.

Don’t take this medicine for longer than three weeks without talking to your doctor.

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额外的Dosage Information

Your dose will depend on the severity of your pain and the formulation of cyclobenzaprine you’re using.

If you have liver problems, your doctor may try to keep you on a lower dose.

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Secondary Uses

Sometimes, muscle relaxants like cyclobenzaprine are used “off-label” to treat conditions they’re not approved for, such as fibromyalgia.

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Images

751, M

Color: yellow

Shape: round

Form: film coated

Imprint: 751, M

M, 761

Color: white

Shape: round

Form: film coated

Imprint: M, 761

M, 771

Color: blue

Shape: round

Form: film coated

Imprint: M, 771

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Medical Disclaimer

Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health.
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