Idursulfase (Elaprase)
Idursulfase contains a natural enzyme that some people lack because of a genetic disorder. Idursulfase helps replace this missing enzyme.
Idursulfase is used to treat some of the symptoms of a genetic condition called Hunter's syndrome, also called mucopolysaccharidosis (MYOO-koe-pol-ee-SAK-a-rye-DOE-sis).
猎人综合征是一种代谢紊乱，其中身体缺乏酶需要分解某些天然物质所需的酶。这些物质可以在身体中积聚，导致弹性的器官，骨骼异常，面部特征的变化，呼吸问题，心脏问题，视力丧失以及精神或身体能力的变化。
Idursulfase may improve walking ability in people with this condition. However,this medication is not a cure for Hunter syndrome.
Idursulfase may also be used for purposes not listed in this medication guide.
用途
What isIdursulfase (Elaprase)used for?
- Mucopolysaccharidosis Type II
警告
What is the most important information I should know aboutIdursulfase (Elaprase)?
如果您对Idursulfase过敏，您不应该收到此药物。
Tell your doctor if you have asthma or any other lung problems. An allergic reaction could trigger sudden breathing problems.
您的名字可以在使用此药物时在猎人结果调查中列出。本登记处的目的是追踪这种疾病的进展以及IDUsulfase对长期治疗的影响。
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.
Side Effects
What are the side effects ofIdursulfase (Elaprase)?
Some side effects may occur during the idursulfase infusion, or up to 24 hours afterward. Get emergency medical help if you havesigns of an allergic reaction: feeling like you might pass out; hives; trouble breathing, seizure (convulsions); swelling of your face, lips, tongue, or throat.
If you ever have an allergic reaction to idursulfase, you will be watched closely after receiving this medicine again.
Common side effects may include:
- 呕吐，腹泻;
- headache;
- 肌肉或关节疼痛;
- fever, cough;
- itching, rash; or
- flushing (warmth, redness, or tingly feeling).
这不是一个complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeIdursulfase (Elaprase)if I’m pregnant or breastfeeding?
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.
互动
What drugs and food should I avoid while takingIdursulfase (Elaprase)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to takeIdursulfase (Elaprase)?
UseIdursulfase (Elaprase)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Idursulfase is given as an infusion into a vein. A healthcare provider will give you this injection, usually once per week.
必须缓慢地给出这种药，输注最多需要3个小时才能完成。
Your doctor may also prescribe other medications to help prevent an allergic reaction to idursulfase.Take all of your medications as directed.
Your doctor will need to check your progress on a regular basis.
Call your doctor for instructions if you miss an appointment for your idursulfase injection.
Overdose Signs
What happens if I overdose onIdursulfase (Elaprase)?
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.