Istodax(Intravenous)
Romidepsin is used to treat T-cell lymphoma affecting the skin (cutaneous T-cell lymphoma).
Romidepsin is given after at least one other cancer treatment did not work or has stopped working.
romidepsin也可以用于本药物指南中未列出的目的。
用途
What isIstodax(Intravenous)用于？
- 皮肤T细胞淋巴瘤
- 周围T细胞淋巴瘤
警告
What is the most important information I should know aboutIstodax(Intravenous)?
Tell your doctor if you have ever had:
- heart problems or a heart rhythm disorder;
- long QT syndrome (in you or a family member);
- kidney disease;
- liver disease (especially hepatitis B);
- 电解质不平衡（例如，血液中的钾或镁水平高或低）；或者
- 如果您患有恶心，呕吐或腹泻。
You may need to have a negative pregnancy test 7 days before starting this treatment.
使用这种药物的男人和女人都应使用有效的节育来防止怀孕。Men should use condoms. Romidepsin can harm an unborn baby if the mother or father is using this medicine.
Keep using birth control for at least 1 month after your last dose. Tell your doctor right away if a pregnancy occurs.
romidepsin可以使荷尔蒙的节育效果降低，包括避孕药，注射剂，植入物，皮肤斑块和阴道环。使用屏障节育来预防妊娠：避孕套，隔膜，宫颈帽或避孕海绵。
Pregnancy may be less likely to occur while the mother or the father is using this medicine.Both men and women should still use birth control to prevent pregnancy because the medicine can harm an unborn baby.
您不应在使用这种药物时和上次剂量后至少1周内母乳喂养。
Side Effects
什么是副作用Istodax(Intravenous)?
如果有紧急医疗帮助signs of an allergic reaction:hives; difficult breathing; swelling of your face, lips, tongue, or throat.
You may get infections more easily, even serious or fatal infections, during and after treatment.Call your doctor right away if you have signs of infection such as:
- 发烧，流感症状，肌肉疼痛；
- worsening skin symptoms;
- burning when you urinate; or
- 咳嗽，胸部不适，感觉不到呼吸。
Also call your doctor at once if you have:
- chest pain, feeling short of breath;
- 快速或跳动的心跳，胸口颤抖，突然头晕（就像您可能昏倒的一样）；
- low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath;
- signs of tumor cell breakdown--tiredness, weakness, muscle cramps, nausea, vomiting, diarrhea, fast or slow heart rate, tingling in your hands and feet or around your mouth.
Common side effects may include:
- low blood cells counts, infections;
- nausea, vomiting, loss of appetite;
- constipation;
- 瘙痒;
- 疲倦或者
- changes in your sense of taste.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
怀孕和母乳喂养
Can I takeIstodax(Intravenous)if I’m pregnant or breastfeeding?
You may need to have a negative pregnancy test 7 days before starting this treatment.
romidepsin可以使荷尔蒙的节育效果降低，包括避孕药，注射剂，植入物，皮肤斑块和阴道环。使用屏障节育来预防妊娠：避孕套，隔膜，宫颈帽或避孕海绵。
您不应在使用这种药物时和上次剂量后至少1周内母乳喂养。
互动
What drugs and food should I avoid while takingIstodax(Intravenous)?
遵循医生关于食物，饮料或活动的任何限制的指示。
Dosage Guidelines & Tips
How to takeIstodax(Intravenous)?
UseIstodax(Intravenous)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Romidepsin is injected into a vein by a healthcare provider.
This medicine must be given slowly over 4 hours.
Romidepsin is given in a 28-day treatment cycle. You will receive an injection only on certain days of this cycle.
You may be given other medicine to prevent nausea or vomiting while you are receiving romidepsin.
Drink plenty of liquids in the 3 days after each injection.
You may get infections more easily, even serious or fatal infections.You will need frequent medical tests. Your heart function may also need to be checked
If you've had hepatitis B, it may come back or get worse.停止后几个月，您可能需要进行肝功能测试。
Call your doctor for instructions if you miss an appointment for your romidepsin injection.