Bempedoic acid and ezetimibe is a combination medicine that is used to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL).
Bempedoic acid and ezetimibe is used together with a low-fat diet and other medicines to lower LDL cholesterol in adults with an inherited form of high cholesterol. This medicine is also used in adults with heart disease who need additional lowering of LDL cholesterol.
It is not known whether this medicine reduces your risk of heart attack, stroke, or death.
Bempedoic acid and ezetimibe may also be used for purposes not listed in this medication guide.
uses
What isNexlizet(Oral)used for?
- Heterozygous Familial Hypercholesterolemia
- Cardiovascular Risk Reduction
warnings
What is the most important information I should know aboutNexlizet(Oral)?
You should not use this medicine if you are allergic to bempedoic acid or ezetimibe.
You may not be able to use bempedoic acid and ezetimibe if you have severe liver or kidney disease, or if you are on dialysis.
This medicine may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the arm, shoulder, or Achilles' tendon of the heel. This can happen during treatment or several weeks after you start taking bempedoic acid and ezetimibe. Tendon problems may be more likely if you are older than 60, if you have kidney failure, if you already have tendon problems, or if you use steroid medicine or certain antibiotics (such as Cipro or Levaquin).
Tell your doctor if you have ever had:
- 肌腱的问题;
- gout;
- liver disease; or
- kidney disease.
It is not known whether this medicine will harm an unborn baby.Tell your doctor right away if you become pregnant.
You should not breastfeed while using this medicine.
Bempedoic acid and ezetimibe is not approved for use by anyone younger than 18 years old.
User Reviews & Rating
Overall rating forNexlizet(Oral)
Side Effects
What are the side effects ofNexlizet(Oral)?
Get emergency medical help if you havesigns of an allergic reaction:hives, rash, severe itching, skin redness or swelling; wheezing, difficult breathing, feeling light-headed; fast or pounding heartbeats; swelling of your face, lips, tongue, or throat.
Some side effects of bempedoic acid and ezetimibe can occur weeks or months after you have started taking this medicine.
Stop taking this medicine and get medical help right away if you havesigns of tendon rupture--sudden pain, swelling, bruising, tenderness, stiffness, movement problems, or a snapping or popping sound in any of your joints (rest the joint until you receive medical care or instructions).
打电话给你维octor at once if you have:
- low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet; or
- symptoms of gout--joint pain or swelling, warmth or redness around your joints, severe foot or toe pain.
Common side effects may include:
- stomach pain, diarrhea;
- anemia;
- cough, chest tightness, shortness of breath;
- muscle spasm, back pain, joint pain;
- pain in your shoulder, arms, or legs;
- abnormal liver function tests;
- tiredness; or
- cold or flu symptoms such as fever, chills, body aches, stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeNexlizet(Oral)if I’m pregnant or breastfeeding?
It is not known whether this medicine will harm an unborn baby.Tell your doctor right away if you become pregnant.
You should not breastfeed while using this medicine.
Interactions
What drugs and food should I avoid while takingNexlizet(Oral)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to takeNexlizet(Oral)?
UseNexlizet(Oral)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
You may take this medicine with or without food.
Swallow the tablet whole and do not crush, chew, or break it.
You will need frequent medical tests.
Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative.
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.Do nottake two doses at one time.
Overdose Signs
What happens if I overdose onNexlizet(Oral)?
Images
818, ESP
Color: blue
Shape: oval
Imprint: 818, ESP