Nucala Prefilled Syringe(Subcutaneous)
米epolizumab is a monoclonal antibody that works by reducing levels of eosinophils (a type of white blood cell). High eosinophil levels can contribute to certain disorders.
米epolizumab is used to help prevent flare-ups or reduce symptoms of high eosinophil levels (hypereosinophilic syndrome, or HES) in adults and children at least 12 years old.
米epolizumab is also used in adults to help control symptoms and reduce flares of a rare autoimmune disorder called eosinophilic granulomatosis with polyangiitis (EPGA).
米epolizumab is also used together with other medicines to help control severe asthma in adults and children who are at least 6 years old.米epolizumab is not a rescue medicine for asthma attacks.
米epolizumab may also be used for purposes not listed in this medication guide.
uses
What isNucala Prefilled Syringe(Subcutaneous)used for?
- Asthma -- Maintenance
- Wegener's Granulomatosis
warnings
What is the most important information I should know aboutNucala Prefilled Syringe(Subcutaneous)?
You should not use mepolizumab if you are allergic to it.
米epolizumab is not approved for use by a child younger than 6 years old. Mepolizumab should not be used to treat HES in anyone younger than 12 years old, or EPGA in anyone younger than 18 years old.
Tell your doctor if:
- you also use steroid asthma medication;
- you have a history of parasite infection (such as roundworms or tapeworms); or
- you have a history of herpes zoster (also called shingles).
You may be given a zoster (shingles) vaccine before you start using mepolizumab.
If you also use an oral or inhaled steroid medication, you should not stop using it suddenly.Follow your doctor's instructions about tapering your dose.
Tell your doctor if you are pregnant.Your name may be listed on a pregnancy registry to track the effects of mepolizumab on the baby.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
Side Effects
What are the side effects ofNucala Prefilled Syringe(Subcutaneous)?
Get emergency medical help if you havesigns of an allergic reaction:hives, rash; wheezing, chest tightness, difficult breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat.
马上打电话给你的医生如果你有:
- unusual pain or tiredness;
- burning or tingling anywhere in your body; or
- a red or blistering skin rash.
Common side effects may include:
- headache;
- feeling tired;
- back pain; or
- pain, swelling, redness, burning, or itching where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeNucala Prefilled Syringe(Subcutaneous)if I’m pregnant or breastfeeding?
Tell your doctor if you are pregnant.Your name may be listed on a pregnancy registry to track the effects of mepolizumab on the baby.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
Interactions
What drugs and food should I avoid while takingNucala Prefilled Syringe(Subcutaneous)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to takeNucala Prefilled Syringe(Subcutaneous)?
UseNucala Prefilled Syringe(Subcutaneous)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Your doctor may perform blood tests to make sure you do not have conditions that would prevent you from safely using mepolizumab.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
米epolizumab is not a rescue medicine for asthma attacks.Use only fast-acting inhalation medicine for an attack. Seek medical attention if your breathing problems get worse quickly, or if you think your asthma medications are not working as well.
米epolizumab is injected under the skin, usually once every 4 weeks. A healthcare provider may teach you how to properly use the medication by yourself. Follow all directions on your prescription label
米epolizumab powder must be mixed with a liquid (diluent) before using it.Read and carefully follow any Instructions for Use provided with your medicine.Ask your doctor or pharmacist if you don't understand all instructions.
Gently swirl butdo not shake the mixed medicine. Prepare an injection only when you are ready to give it.Do not use if the medicine has changed colors or has particles in it.Call your pharmacist for new medicine.
Store thevial (bottle)in its original carton at room temperature. Protect from light and do not freeze.
Store theprefilled syringeorautoinjectorin the original carton in a refrigerator. Do not freeze or shake the medicine.After removing the medicine from the carton, you must use the syringe or autoinjector within 8 hours.
You may store the prefilled syringe or autoinjector in the unopened carton at room temperature for up to 7 days.Throw away a syringe or autoinjector left out of the refrigerator for more than 7 days.
Each vial, prefilled syringe, or autoinjector is for one use only. Throw it away after one use, even if there is still medicine left inside.
Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.
Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.Do notuse two doses at one time.