Nintedanib用于导致疤痕组织（纤维化）在肺部深处形成的疾病患者。疤痕组织会随着时间的流逝而变稠并变得僵硬，这可能会使您的肺部工作更困难。肺功能降低会使您难以呼吸。当您的大脑，心脏和其他器官无法获得足够的氧气时，可能会发生其他医疗问题。
Nintedanib is used to treat a lung disease called idiopathic pulmonary fibrosis (IPF).
Nintedanib is also used to treat chronic (long lasting) interstitial lung disease in which the scar tissue keeps getting worse.
Nintedanib is also used to slow the decline in lung function in people with a disorder called systemic sclerosis-associated interstitial lung disease (sometimes called scleroderma-associated ILD).
Nintedanib不能治愈IPF或ILD，但是这种药物可以减慢这些疾病对肺部的影响。
Nintedanib may also be used for purposes not listed in this medication guide.
用途
What isOfev (Nintedanib)用于？
- Idiopathic Pulmonary Fibrosis
- 慢性肺部病
警告
我应该知道的最重要的信息是什么Ofev (Nintedanib)?
告诉医生您是否曾经有：
- liver disease;
- 心脏问题;
- 血块；
- bleeding problems (in you or a family member);
- surgery on your stomach or intestines;
- 憩室炎；
- if you smoke; or
- 如果您服用较薄的血液，例如华法林（Coumadin，Jantoven）。
在开始此治疗之前，您可能需要进行负妊娠测试。
Nintedanib会导致未出生的婴儿出生缺陷或死亡。利用effective birth control to prevent pregnancy while you are using this medicine and for at least 3 months after your last dose. Tell your doctor if you become pregnant.
如果您使用荷尔蒙节育措施（避孕药，注射剂，植入物，皮肤斑块或阴道环），也使用屏障形式的避孕药形式，以防止服用Nintedanib时怀孕。屏障形式包括避孕套，隔膜，宫颈帽或避孕海绵）。
Nintedanib may affect fertility (your ability to have children) in women. However,重要的是要使用节育来预防怀孕，因为这种药物会损害未出生的婴儿。
使用这种药物时，您不应母乳喂养。
Nintedanib is not approved for use by anyone younger than 18 years old.
利用r Reviews & Rating
Overall rating forOfev (Nintedanib)
Side Effects
什么是副作用Ofev (Nintedanib)?
如果有紧急医疗帮助signs of an allergic reaction:麻疹;呼吸困难；脸部，嘴唇，舌头或喉咙肿胀。
Call your doctor at once if you have:
- 严重的恶心，呕吐或腹泻；
- 严重的胃痛，腹胀或压痛；
- bleeding from your rectum or blood in your stools;
- easy bruising or bleeding, any wound that will not heal;
- fever, chills, cough with mucus, chest pain, feeling short of breath;
- heart attack symptoms- 胸痛或压力，疼痛散布在下巴或肩膀上，恶心，出汗；
- 肝脏问题- 胃疼痛（右上角），食欲不振，疲倦，深色尿液，黄疸（皮肤或眼睛发黄）；或者
- 中风的迹象--sudden numbness or weakness (especially on one side of the body), slurred speech, problems with vision or balance.
Liver problems may be more likely in women, in people who weigh less than 143 pounds (65 kilograms), and in people of Asian descent.
Your doses may be delayed if you have certain side effects.
常见的副作用可能包括：
- nausea, vomiting, loss of appetite;
- stomach pain;
- 腹泻，体重减轻；
- increased blood pressure;
- 头痛;或者
- 肝功能异常测试。
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
怀孕和母乳喂养
我能拿吗Ofev (Nintedanib)如果我怀孕还是母乳喂养？
在开始此治疗之前，您可能需要进行负妊娠测试。
Nintedanib会导致未出生的婴儿出生缺陷或死亡。利用effective birth control to prevent pregnancy while you are using this medicine and for at least 3 months after your last dose. Tell your doctor if you become pregnant.
如果您使用荷尔蒙节育措施（避孕药，注射剂，植入物，皮肤斑块或阴道环），也使用屏障形式的避孕药形式，以防止服用Nintedanib时怀孕。屏障形式包括避孕套，隔膜，宫颈帽或避孕海绵）。
Nintedanib may affect fertility (your ability to have children) in women. However,重要的是要使用节育来预防怀孕，因为这种药物会损害未出生的婴儿。
使用这种药物时，您不应母乳喂养。
互动
What drugs and food should I avoid while takingOfev (Nintedanib)?
Smoking can make nintedanib less effective. Avoid smoking while taking this medicine, or try to quit before you start this treatment.
Avoid taking an herbal supplement containing St. John's wort.
在服用非甾体类抗炎药（NSAID）之前，请询问您的医生，例如阿司匹林，布洛芬（Advil，Motrin），Naproxen（Aleve），Celecoxib（celebrex），双氯芬酸，吲哚美辛，印米甲发现，美昔康，Meloxicam等。与Nintedanib一起使用NSAID可能会导致您容易瘀伤或流血。
Dosage Guidelines & Tips
How to takeOfev (Nintedanib)?
利用Ofev (Nintedanib)完全按照标签或医生的规定。不要在较大或较小的量或更长的时间内使用。
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using nintedanib.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Take with food and a full glass of water.
吞下胶囊，不要粉碎，咀嚼，破裂或打开。
定期服用剂量，通常每12小时一次。
Nintedanib can cause severe diarrhea, which can be life-threatening if it leads to dehydration. You may need to take medication to prevent or quickly treat diarrhea.
您的医生可能建议您在服用Nintedanib时始终提供抗diarhea药物，例如loperamide（imodium）。按照标签上的指示或医生的规定，服用抗diarhea药物。
如果您在服用nintedanib时患有腹泻，请喝大量液体，并立即致电您的医生。
你需要频繁的医学测试,以确保倪ntedanib is not causing harmful effects on your liver. Your next few doses may be delayed based on the results.
Store this medicine in the original container at room temperature, away from moisture and heat.
Skip the missed dose and use your next dose at the regular time.不要use two doses at one time.
Overdose Signs
What happens if I overdose onOfev (Nintedanib)?
不要take more than 300 milligrams of nintedanib in one day.
Images
徽标150
Color： 棕色的
形状: capsule
烙印: LOGO 150
LOGO 100
Color: peach
形状: capsule
烙印：徽标100