Onpattro(Intravenous)
Patisiran is used to treat polyneuropathy (damage of multiple nerves throughout the body) in adults with hereditary transthyretin-mediated amyloidosis (hATTR).
Patisiran may also be used for purposes not listed in this medication guide.
uses
What isOnpattro(Intravenous)used for?
- Amyloidogenic Transthyretin Amyloidosis
warnings
What is the most important information I should know aboutOnpattro(Intravenous)?
Before using patisiran tell your doctor about all your medical conditions or allergies.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of patisiran on the baby.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
Side Effects
What are the side effects ofOnpattro(Intravenous)?
Get emergency medical help if you havesigns of an allergic reaction:hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your caregiver if you feel warm, dizzy, nauseated, light-headed, or have a headache, fast heartbeats, swelling in your face, stomach pain, chest pain, or trouble breathing.
Common side effects may include:
- cold symptoms such as stuffy nose, sneezing, sore throat.
这不是一个侧eff的完整列表ects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeOnpattro(Intravenous)if I’m pregnant or breastfeeding?
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of patisiran on the baby.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
Interactions
What drugs and food should I avoid while takingOnpattro(Intravenous)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to takeOnpattro(Intravenous)?
UseOnpattro(Intravenous)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Patisiran is given as an infusion into a vein. A healthcare provider will give you this injection once every 3 weeks.
This medicine must be given slowly, and the infusion can take about 80 minutes to complete.
Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when patisiran is injected.
You may be given other medications to help prevent serious side effects or an infusion reaction.
Your doctor may have you take extra vitamin A while you are using patisiran. Take only the amount of vitamin A your doctor has prescribed, especially if you are pregnant.An overdose of vitamin A can cause vision problems or other serious side effects.
Call your doctor at once if you have vision problems (especially at night) while you are taking vitamin A.
Patisiran doses are based on weight. Your dose needs may change if you gain or lose weight.
You may need frequent medical tests. Even if you have no symptoms, tests can help your doctor determine if this medicine is effective. You may also need frequent eye exams.
Call your doctor for instructions if you miss an appointment for your patisiran injection.
Overdose Signs
What happens if I overdose onOnpattro(Intravenous)?
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.