Ravulizumab(Intravenous)
Rawulizumab用于治疗成人和儿童的阵发性夜间血红蛋白（PNH）至少1个月大。
Rawulizumab还用于治疗罕见的慢性血液疾病，称为非典型溶血性尿毒症综合征（Ahus）至少1个月大。这种药是not for usein treating HUS that is related to Shiga toxin E. coli.
Ravulizumab is available only under a special program. You must be registered in the program and understand the risks and benefits of this medicine.
Ravulizumab也可用于本药物指南中未列出的目的。
warnings
什么是the most important information I should know aboutRavulizumab(Intravenous)还
如果您对其过敏，如果您有脑膜炎球菌感染（如脑膜炎或败血症），或者如果您目前没有针对脑膜炎的疫苗接种（除非延迟治疗的风险超过脑膜炎的风险，则不得用rawulizumab治疗）。
在开始使用Rawulizumab之前，您需要在至少2周内获得疫苗以防止脑膜炎球菌感染。如果您的孩子被ravulizumab对待，请确保他或她接种肺炎和流感B（HIB）疫苗。
如果您需要在接种疫苗之前开始接受此药，you may be given antibiotic medicine to take during the first 2 weeks of ravulizumab treatment.
告诉你的医生如果你最近有任何感染症状（发烧，寒冷或流感症状）。
告诉你的医生如果你怀孕了。我s not known whether ravulizumab will harm an unborn baby. However, having PNH during pregnancy may cause complications in the baby or the mother, including blood clots, infections, bleeding, miscarriage, premature delivery, or death. The benefit of treating PNH may outweigh any risks to the baby or the mother.
使用ravulizumab时不要母乳喂养，and for at least 8 months after your last dose.
Not approved for use by anyone younger than 1 month old.
副作用
What are the side effects ofRavulizumab(Intravenous)还
Get emergency medical help if you have过敏反应的迹象：hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your caregiver if you feel light-headed or if you have chest pain, trouble breathing, or swelling in your face.
如果您有感染迹象，请立即致电您的医生，例如：
- 肌肉疼痛与流感样症状;
- fever and a rash;
- fever and a headache;
- headache and stiffness in your neck or back;
- 头痛和恶心或呕吐;
- confusion; or
- 你的眼睛对光线可能更敏感。
如果你有淋病的症状，请致电你的医生，例如：
- pain or burning when you urinate;
- pain or swelling of the genital or rectal area;
- 不寻常的阴道出血;要么
- 从阴茎或阴道排出。
如果您停止使用Ravulizumab，请告诉您的医生，如果您有任何新的或恶化的症状，例如：疲倦，混乱，胃痛，胸痛，呼吸或吞咽麻烦，（男性）麻烦在你的尿液中有勃起，癫痫发作或意识丧失。
Common side effects may include:
- fever;
- 高血压;
- 腹泻，恶心，呕吐;
- headache; or
- cold symptoms such as stuffy nose, sneezing, sore throat.
这不是一个完整的副作用列表，其他可能会发生。打电话给您的医生，征求有关副作用的医疗建议。您可以在1-800-FDA-1088向FDA报告副作用。
Pregnancy & Breastfeeding
Can I takeRavulizumab(Intravenous)if I’m pregnant or breastfeeding?
告诉你的医生如果你怀孕了。我s not known whether ravulizumab will harm an unborn baby. However, having PNH during pregnancy may cause complications in the baby or the mother, including blood clots, infections, bleeding, miscarriage, premature delivery, or death. The benefit of treating PNH may outweigh any risks to the baby or the mother.
使用ravulizumab时不要母乳喂养，and for at least 8 months after your last dose.
Interactions
在服用时，我应该避免哪些药物和食物Ravulizumab(Intravenous)还
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
剂量指南和提示
如何服用Ravulizumab(Intravenous)还
UseRavulizumab(Intravenous)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
请遵循处方标签上的所有方向，阅读所有药物指南或说明书。完全按照指示使用药物。
If you've been using another drug called eculizumab (Soliris), you will need to wait 2 weeks after your last dose of eculizumab before starting treatment with ravulizumab.
Ravulizumab通过医疗保健提供者注入静脉。前两个输注通常相隔2周，然后每4-8周再次输注一次。
每次输注后，您将密切关注至少1小时以确保您没有过敏反应。
剂量基于重量。如果您获得或减肥，您的剂量可能会发生变化。
您可能更容易发生感染，甚至严重或致命的感染。You will need frequent medical tests.
阅读有关严重感染的患者安全卡and the symptoms to watch for. Keep this card with you at all times while using ravulizumab and for at least 8 months after your last dose.Your infection risk could last for several months after you stop using ravulizumab.
Some people may have an increased risk of gonorrhea (a sexually transmitted disease). Talk with your doctor about safe ways to keep from getting an infection during sex.
即使在你停止使用这种药后，Ravulizumab也会对你的身体持久影响。如果你有pnh，你停止使用ravulizumab，您的医生可能需要在上次剂量后至少16周检查您的进度。如果你有Ahus，你停止使用ravulizumab，您的医生可能需要在上次剂量后至少12个月内检查您。
如果您错过了ravulizumab注射的预约，请致电您的医生。
过量标志
如果我过量发作，会发生什么Ravulizumab(Intravenous)还
在医疗环境中，将迅速处理过量。