Rebif(Subcutaneous)
Interferon beta-1a is used to treat relapsing forms of multiple sclerosis in adults (including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease).
This medicine will not cure MS, it will only decrease the frequency of relapse symptoms.
Interferon beta-1a may also be used for purposes not listed in this medication guide.
warnings
什么是the most important information I should know aboutRebif(Subcutaneous)还
如果您对天然或重组干扰素β或白蛋白过敏，您不应该使用这种药。
Tell your doctor if you have ever had:
- 出血问题或血凝块;
- depression, mental illness, or suicidal thoughts or actions;
- liver disease;
- bleeding problems;
- low blood cell counts;
- 心脏病;
- 甲状腺障碍;
- 乳胶过敏;
- an autoimmune disorder such as rheumatoid arthritis, lupus, or psoriasis;
- a seizure; or
- 如果你喝酒。
一些品牌的干扰素β-1a含有捐赠的人血浆，可含有病毒或其他传染病。测试并治疗捐赠的血浆以降低污染的风险，但它仍然可以传播疾病的可能性。向医生询问任何可能的风险。
Tell your doctor if you are pregnant or plan to become pregnant, or if you are breastfeeding.
干扰素Beta-1A未被批准用于18岁的人。
Side Effects
What are the side effects ofRebif(Subcutaneous)还
Get emergency medical help if you have过敏反应的迹象（hives, itching, anxiety, difficult breathing, swelling in your face or throat)或者a severe skin reaction（fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
干扰素β-1A可以导致你的器官内的小血管中的危及生命的血液凝块，例如你的大脑或肾脏。Seek medical help right away if you have symptoms of this condition, such as a fever, tiredness, decreased urination, bruising, or nosebleeds.
如果你有话，请立即打电话给医生：
- 给出注射的疼痛，肿胀，瘀伤，发红，渗出或皮肤变化;
- a light-headed feeling, like you might pass out;
- 情绪或行为的不寻常变化（感到绝望，焦虑，紧张，烦躁或抑郁）;
- 关于自杀或伤害自己的想法;
- 易瘀伤，异常出血;
- a seizure;
- heart problems--swelling, rapid weight gain, feeling short of breath, rapid heartbeats, chest pain spreading to your jaw or shoulder, nausea, sweating;
- liver problems- usea，食欲不振，疲倦，混乱，易瘀伤或出血，暗尿，粘土凳子或黄疸（染色或眼睛泛黄）;
- signs of infection--fever，寒冷，咳嗽，用粘液，血腥腹泻，疼痛或燃烧时尿酸尿剂;或者
- 甲状腺问题- 各种各样的秋千，睡眠，疲倦，饥饿，腹泻，冲击心跳，肌肉无力，出汗，干燥的皮肤，稀薄的头发，月经变化，体重变化，脸上的浮肿，对热或寒冷的温度更敏感。
Common side effects may include:
- low blood cell counts;
- skin changes where the injection was given;
- 沮丧;
- abnormal liver function tests;
- 肚子痛;或者
- flu symptoms--headache, fever, chills, chest pain, back pain, tiredness, weakness, muscle aches.
这不是一个副作用,ot的完整列表hers may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeRebif(Subcutaneous)if I’m pregnant or breastfeeding?
Tell your doctor if you are pregnant or plan to become pregnant, or if you are breastfeeding.
Interactions
在服用时，我应该避免哪些药物和食物Rebif(Subcutaneous)还
避免将该药物注入红色，瘀伤，刺激，疤痕或感染的皮肤。
剂量指南和提示
如何服用Rebif(Subcutaneous)还
UseRebif(Subcutaneous)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
请遵循处方标签上的所有方向，阅读所有药物指南或说明书。你的医生可能偶尔会改变你的剂量。完全按照指示使用药物。
Interferon beta-1a is given by injection. A healthcare provider may teach you how to properly use the medication by yourself.
阅读并仔细遵循您的药物提供的任何说明。Ask your doctor or pharmacist if you don't understand all instructions.
Avonex is injected into a muscle,通常每周一次，每周的同一天（如每周一）。
Rebif is injected under the skin,usually 3 times per week (such as Monday, Wednesday, and Friday) at the same time on each dosing day.
这powder form of this medicine must be mixed with a liquid (diluent) before using it. Prepare an injection only when you are ready to give it.Do not use if the medicine has changed colors or has particles in it.致电你的药剂师进行新药。
您的护理提供者将向您展示身体在哪里注入干扰素Beta-1a。每次注射时都会使用不同的地方。不要连续两次注入同一个地方。
注射后大约2小时，检查皮肤发红，肿胀或疼痛，在那里给予注射。Call your doctor if you have a skin reaction that does not go away within a few days.
This medicine can cause flu-like symptoms, especially when you first start using it. You may be given other medications to help prevent these symptoms. Keep using these medicines for as long as your doctor has prescribed.
您需要频繁的医疗测试。
每个预先填写的注射器或注射笔仅用于一次使用。一次使用后扔掉它，即使里面还有留下的药。
将这种药物存放在冰箱里。保护光线，不要冻结。
混合后powder具有稀释剂的干扰素β-1a的形式，将混合物储存在冰箱中并在6小时内使用。
这Avonex预填充注射器或自动注射器may be removed from the refrigerator about 30 minutes before your injection, to reach room temperature.在热水下不要温暖药物。
You may also store interferon beta-1a for a short time at cool room temperature protected from light.
- Do not leave theAvonex预填充注射器或自动注射器从冰箱中超过7天。
- Do not leave theAvonex小瓶或者theRebif prefilled syringe or autoinjectorout of a refrigerator for longer than a total of 30 days.
不要冻结干扰素beta-1a，如果它已经变得冷冻，请扔掉药物。
Each vial, syringe, or autoinjector is for one use only. Throw it away after one use, even if there is still medicine left inside.
只需一次使用针和注射器，然后将它们放在刺穿的“Sharps”容器中。遵循州或地方法律关于如何处理这个容器。让它远离儿童和宠物。
对于Avonex：尽快使用药物，但不要连续两天注射Avonex。Do not一次使用两剂。
For Rebif:Call your doctor for instructions if you miss a dose.