Repatha Pushtronex(Subcutaneous)
Evolocumab.works by helping the liver reduce levels of "bad" cholesterol (low-density lipoprotein, or LDL) circulating in your blood.
Evolocumab与纯合或杂合子家族高胆固醇血症（遗传类型的高胆固醇）的人中的低脂饮食和其他胆固醇降低药物一起使用。这些条件会导致LDL胆固醇的高血液水平，并且还可以引起斑块在动脉内部积聚。
Evolocumab还用于帮助降低斑块或血管在动脉中的斑块堆积或硬化引起的心脏或血管问题中卒中，心脏病或其他心脏并发症的风险（也称为动脉粥样硬化或动脉硬化）。
Evolocumab.may also be used for purposes not listed in this medication guide.
uses
什么是Repatha Pushtronex(Subcutaneous)used for?
- 高脂血症
- 纯合家族高胆固醇血症
- Cardiovascular Risk Reduction
warnings
什么是the most important information I should know aboutRepatha Pushtronex(Subcutaneous)还
如果你对它过敏，你不应该使用Evolocumab。
Tell your doctor if you have ever had:
- liver or kidney disease; or
- 乳胶过敏。
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of evolocumab on the baby.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
没有医疗建议，不要把这种药给孩子。Evolocumab未经13岁的人未被批准使用。对于某些条件，不应向任何年龄的孩子提供Evolocumab。
副作用
What are the side effects ofRepatha Pushtronex(Subcutaneous)还
Get emergency medical help if you have过敏反应的迹象：荨麻疹，严重瘙痒;呼吸困难;你的脸，嘴唇，舌头或喉咙肿胀。
如果你有话，请立即打电话给医生：
- high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor.
Common side effects may include:
- 给出注射的发红，疼痛或瘀伤;
- 背痛;
- flu symptoms; or
- cold symptoms such as stuffy nose, sneezing, sore throat.
这不是一个完整的副作用列表，其他可能会发生。打电话给您的医生，征求有关副作用的医疗建议。您可以在1-800-FDA-1088向FDA报告副作用。
Pregnancy & Breastfeeding
Can I takeRepatha Pushtronex(Subcutaneous)if I’m pregnant or breastfeeding?
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of evolocumab on the baby.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
Interactions
在服用时，我应该避免哪些药物和食物Repatha Pushtronex(Subcutaneous)还
不要将Evolocumab注入瘀伤，疼痛，疤痕或硬化的皮肤中。
剂量指南和提示
如何服用Repatha Pushtronex(Subcutaneous)还
UseRepatha Pushtronex(Subcutaneous)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
遵循处方标签上各个方向nd read all medication guides or instruction sheets. Use the medicine exactly as directed.
Evolocumab注入皮肤下。医疗保健提供者可以教你如何自己正确使用药物。
Evolocumab在预先填写的注射器中提供，SECLICK预填充自动注射器或带有预先填充墨盒的Pushtronex On-Body Infusor。阅读并仔细遵循您的药物提供的任何说明。Ask your doctor or pharmacist if you have questions, or call the manufacturer at 1-844-737-2842.
这Pushtronex.on-body infusor is a special device placed on the skin that delivers your evolocumab dose slowly. You will need to wear the device for about 9 minutes to get the full dose. While wearing the on-body infusor, you may perform moderate activities such as walking, bending, or reaching.
Your care provider will show you the best places on your body to inject evolocumab or place the on-body infusor. Use a different place each time you give an injection. Do not inject into the same place two times in a row.
每次使用预填充注射器，盒式磁带或注射装置都仅用于一次使用。一次使用后扔掉，即使里面还有一些药物。遵循关于扔掉使用的针和注射器的任何州或地方法律。使用防刺穿的“锐布”容器。遵循州或地方法律关于如何处理这个容器。让它远离儿童和宠物。
Store evolocumab in the refrigerator in its original carton and protect from light and heat.不要冻结。扔掉任何被冻结的Evolocumab。
将药物从冰箱中脱离，并在注射剂量之前让它达到30至45分钟的室温。不要加热注射器或注射装置。
您还可以将EvoloDumab储存在原始纸箱上，冷却室温，远离光线和热量。如果在室温下在30天内使用药物。
仔细处理这种药。滴注射装置会导致它破裂。即使你看不到它的休息，请勿使用已经丢弃到硬表面上的注射装置。致电你的药剂师进行新药。
不要摇动这种药。如果药物改变颜色或有颗粒，请勿使用。致电你的药剂师进行新药。
You should not stop using evolocumab without your doctor's advice,或者您的LDL胆固醇水平可能会增加。
Evolocumab只是完整的治疗程序的一部分，还包括饮食，他汀类药物药物和常规验血。密切关注你的医生的指示。
Use the missed dose within 7 days after that injection was due, but skip the missed dose if you are more than 7 days late.After a missed dose, go back to your original schedule and use the medicine again when your next scheduled dose is due.
Do not一次使用两剂。