Rydapt(Oral)
Midostaurin is used together with other cancer medicines to treat acute myeloid leukemia.
Midostaurin is also used to treat certain rare blood disorders, including systemic mastocytosis with mast cell leukemia or other cancers affecting the blood, bone marrow, or lymphatic tissue.
Midostaurin may also be used for purposes not listed in this medication guide.
warnings
What is the most important information I should know aboutRydapt(Oral)?
You should not use midostaurin if you are allergic to it.
Tell your doctor if you have ever had:
- lung disease or breathing problems.
You may need to have a negative pregnancy test before starting this treatment.
Midostaurin can harm an unborn babyif the mother or the father is using this medicine.
- If you are a woman,do not use midostaurin if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 4 months after your last dose. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of midostaurin on the baby.
- If you are a man,use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 months after your last dose.
- Tell your doctor right away if a pregnancy occurs while either the mother or the father is using midostaurin.
This medicine may affect fertility (ability to have children) in both men and women. However,it is important to use birth control to prevent pregnancy because midostaurin can harm an unborn baby.
You should not breastfeed while using this medicine and for at least 4 months after your last dose.
Midostaurin is not approved for use by anyone younger than 18 years old.
Side Effects
What are the side effects ofRydapt(Oral)?
Get emergency medical help if you havesigns of an allergic reaction:hives, warmth, redness, or tingly feeling; chest pain, difficult breathing; swelling of your face, lips, tongue, or throat.
马上打电话给你的医生如果你有:
- pain or sores in or around your mouth, redness inside your mouth, sore throat;
- sudden chest pain or discomfort, wheezing, dry cough, feeling short of breath;
- signs of infection around where a needle was injected to give you other medicines--bruising, swelling, warmth, redness, oozing, or bleeding around the needle;
- high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or
- low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.
Common side effects may include:
- low blood cell counts, fever;
- bruising, nosebleeds;
- high blood sugar;
- infection around a needle injection;
- mouth sores;
- cold symptoms such as stuffy nose, sneezing, sore throat;
- trouble breathing;
- nausea, vomiting, stomach pain, constipation, diarrhea;
- muscle or bone pain;
- headache, feeling tired; or
- swelling in your hands, feet, or ankles.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeRydapt(Oral)if I’m pregnant or breastfeeding?
You may need to have a negative pregnancy test before starting this treatment.
You should not breastfeed while using this medicine and for at least 4 months after your last dose.
Interactions
What drugs and food should I avoid while takingRydapt(Oral)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to takeRydapt(Oral)?
UseRydapt(Oral)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Your doctor will perform a test to make sure midostaurin is the right treatment for your condition.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Midostaurin is usually taken 2 times per day (once every 12 hours) with food.
Take your doses at regular intervals to keep a steady amount of the drug in your body at all times.
You may be given medication to prevent nausea or vomiting while you are taking midostaurin.
如果你呕吐采取midostaurin后不久,做not take another dose. Wait until your next scheduled dose time to take the medicine again.
Do not crush or open a midostaurin capsule.
You may need frequent blood tests (every 1 to 4 weeks). Midostaurin is usually given until your body no longer responds to the medication.
Use all medications as directed by your doctor. Read the instructions provided with each medication.Do not change your doses or medication schedule without your doctor's advice.
Store midostaurin in the original container at room temperature, away from moisture and heat.
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.Do nottake two doses at one time.