Rylaze (Intramuscular)
Rylaze (Intramuscular)
Asparaginase Erwinia chrysanthemi is a cancer medicine.
Erwinazeis used to treat acute lymphoblastic leukemia in adults and children at least 1 year old.
Rylazeis used to treat lymphoblastic lymphoma in adults and children at least 1 month old who have become allergic to other forms of asparaginase such as Elspar or Oncaspar.
Asparaginase Erwinia chrysanthemi may also be used for purposes not listed in this medication guide.
uses
What isRylaze (Intramuscular)used for?
- Acute Lymphoblastic Leukemia
warnings
我应该kn最重要的信息是什么呢ow aboutRylaze (Intramuscular)?
You should not use this medicine if you have received any form of asparaginase in the past and it caused you to have:
- a serious allergic reaction;
- serious pancreas problems;
- a life-threatening blood clot; or
- serious bleeding problems.
Tell your doctor if you have ever had:
- problems with your liver or pancreas;
- bleeding problems;
- a blood clot; or
- diabetes.
May harm an unborn baby.You may need a pregnancy test to make sure you are not pregnant. Use birth control while using this medicine and for at least 3 months after your last dose. Tell your doctor if you become pregnant.
Asparaginase Erwinia chrysanthemi can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. Use barrier birth control to prevent pregnancy: condom, diaphragm, cervical cap, or contraceptive sponge.
Do not breastfeed while using this medicine,and for at least 3 months after your last dose ofErwinazeor 1 week after your last dose ofRylaze.
Side Effects
What are the side effects ofRylaze (Intramuscular)?
Get emergency medical help if you havesigns of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
马上打电话给你的医生如果你有:
- easy bruising or bleeding (nosebleeds, bleeding gums);
- any bleeding that will not stop;
- blisters or ulcers in your mouth, red or swollen gums, trouble swallowing;
- signs of liver or pancreas problems--severe stomach pain (that may spread to your back), nausea or vomiting, jaundice (yellowing of the skin or eyes);
- signs of a blood clot--sudden numbness or weakness (especially on one side of the body), severe headache, chest pain, feeling short of breath, pain or swelling in an arm or leg;
- low white blood cell counts--fever, mouth sores, skin sores, sore throat, cough; or
- high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor.
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common side effects may include:
- liver or pancreas problems;
- bleeding or blood clots;
- high blood sugar;
- stomach pain, loss of appetite, nausea, vomiting, diarrhea;
- fever, headache, tiredness, mouth sores;
- bone pain, muscle or joint pain;
- allergic reaction, skin rash; or
- abnormal liver function tests.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeRylaze (Intramuscular)if I’m pregnant or breastfeeding?
May harm an unborn baby.You may need a pregnancy test to make sure you are not pregnant. Use birth control while using this medicine and for at least 3 months after your last dose. Tell your doctor if you become pregnant.
Asparaginase Erwinia chrysanthemi can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. Use barrier birth control to prevent pregnancy: condom, diaphragm, cervical cap, or contraceptive sponge.
Do not breastfeed while using this medicine,and for at least 3 months after your last dose ofErwinazeor 1 week after your last dose ofRylaze.
Interactions
What drugs and food should I avoid while takingRylaze (Intramuscular)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to takeRylaze (Intramuscular)?
UseRylaze (Intramuscular)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Asparaginase Erwinia chrysanthemi is injected into a muscle or into a vein.Erwinazeis usually given every 48 hours.Rylazeis usually given 3 times per week.
Read and follow all Instructions for Use.Ask your doctor or pharmacist if you need help.
Do not shake the medication bottleor you may ruin the medicine.
Prepare an injection only when you are ready to give it.Call your pharmacist if the medicine has changed colors or has particles in it.
Do not reuse a needle or syringe. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.
Your blood will need to be tested oftenand your dose or medication schedule may be changed based on the results.
Doses are based on body surface area (height and weight). Your dose may change if you gain or lose weight or if you are still growing.
Store this medicine in the original carton in the refrigerator. Protect from light.
Throw away a vial (bottle) after one use, even if there is still medicine left inside.
Store mixed medicine at room temperature and use it within 4 hours.Do not refrigerate or freeze after mixing.
Call your doctor for instructions if you miss a dose.