Zinecard(Intravenous)
Dexrazoxane is used to protect the heart and other tissues from harmful side effects caused by certain cancer medications.
TheTotectbrand of dexrazoxane is used in men or women to treat a condition called extravasation (es-TRA-va-ZAY-shun). Extravasation happens when an injected medicine escapes from the blood vessels and circulates into tissues in the body. Serious tissue damage can occur when extravasation happens during injection of certain cancer medications.
Dexrazoxane is also used to help prevent chemotherapy-related heart problems in women who are receiving doxorubicin for metastatic breast cancer. This medicine is given only after you have received enough doxorubicin infusions to amount to a certain total dose.
Dexrazoxane may also be used for purposes not listed in this medication guide.
用途
What isZinecard(Intravenous)用于？
- Extravasation
- 心肌病预防
警告
What is the most important information I should know aboutZinecard(Intravenous)?
You should not receiveZinecard如果您的化学疗法不包括多柔比星或类似的药物，如：
- daunorubicin (Cerubidine, Daunoxome);
- epirubicin (Ellence);
- inarubicin（idamycin）;要么
- mitoxantrone (Novantrone).
Tell your doctor if you have ever had:
- heart problems;
- liver disease; or
- 肾脏疾病。
Dexrazoxane can harm an unborn baby or cause birth defectsif the mother or the father is receiving this medicine.Women should use effective birth control to prevent pregnancy while receiving dexrazoxane and for at least 6 months after the last dose. Men should use birth control during treatment and for at least 3 months after the last dose. Tell your doctor right away if a pregnancy occurs during this time.
这种药可能会影响男性的生育率（能力有孩子）。然而，it is important to use birth control to prevent pregnancy because dexrazoxane may harm the baby if a pregnancy does occur.
在使用右销时，你不应该母乳喂养。妇女接受Totectshould continue to not breastfeed for at least 2 weeks after the last dose.
Side Effects
什么是副作用Zinecard(Intravenous)?
如果有的话，获得紧急医疗帮助过敏反应的迹象：hives; difficult breathing; feeling light-headed; swelling of your face, lips, tongue, or throat.
马上打电话给你的医生如果你有:
- fever, chills, tiredness, mouth sores, skin sores;
- 易瘀伤，异常出血;
- sore throat, cough, trouble breathing; or
- 瘀伤，肿胀，温暖，发红，渗出或出血任何手术切口。
Common side effects may include:
- nausea, vomiting;
- 发热;
- infection after a surgery; or
- pain where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
怀孕和母乳喂养
Can I takeZinecard(Intravenous)if I’m pregnant or breastfeeding?
在使用右销时，你不应该母乳喂养。妇女接受Totectshould continue to not breastfeed for at least 2 weeks after the last dose.
互动
What drugs and food should I avoid while takingZinecard(Intravenous)?
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
剂量指南和提示
如何服用Zinecard(Intravenous)?
UseZinecard(Intravenous)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Dexrazoxane is given as an infusion into a vein. A healthcare provider will give you this injection.
Totect通常在外渗后6小时内开始，每天持续3天。
Dexrazoxane is usually started 15 minutes before you receive your doxorubicin infusion. This medicine is not given with your first dose of doxorubicin, but only after you've received prior doxorubicin doses up to a certain total amount.
Dexrazoxane can add to bone marrow suppression caused by chemotherapy.您可能更容易发生感染，甚至严重或致命的感染。Your doctor will need to examine you on a regular basis.
Since dexrazoxane is given by a healthcare professional as part of your chemotherapy treatment, you are not likely to miss a dose.
Call your doctor for instructions if you miss your chemotherapy appointment.