Zykadia(Oral)
Ceritinib is used to treat non-small cell lung cancer that has spread to other parts of the body.
Ceritinib is used only if your cancer has a specific genetic marker. Your doctor will test you for this gene.
Ceritinib may also be used for purposes not listed in this medication guide.
uses
What isZykadia(Oral)used for?
- Non-Small Cell Lung Cancer
warnings
What is the most important information I should know aboutZykadia(Oral)?
You should not use ceritinib if you are allergic to it.
Tell your doctor if you have ever had:
- heart problems;
- long QT syndrome (in you or a family member);
- an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);
- a pancreas disorder;
- diabetes or high blood sugar; or
- liver disease.
Ceritinib can harm an unborn babyif the mother or the father is taking this medicine.
- If you are a woman,do not use ceritinib if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.
- If you are a man,use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.
- Tell your doctor right away if a pregnancy occurs while either the mother or the father is using ceritinib.
You should not breast-feed while using this medicine and for at least 2 weeks after your last dose.
Side Effects
What are the side effects ofZykadia(Oral)?
Get emergency medical help if you havesigns of an allergic reaction:hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Ceritinib usually causes side effects on your stomach (nausea, vomiting, diarrhea, stomach pain) that can be severe.Call your doctor if you have severe or ongoing stomach symptoms.
Also call your doctor at once if you have:
- severe pain in your upper stomach spreading to your back;
- slow heartbeats, weak pulse, weak or shallow breathing;
- sudden chest pain or discomfort, fever, dry cough or cough with mucus, feeling short of breath;
- fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);
- high blood sugar--increased thirst, increased urination, hunger, fruity breath odor, headaches, thinking problems, blurred vision, feeling tired; or
- high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; o
- liver problems--right-sided-stomach pain, loss of appetite, unusual tiredness, itching, easy bruising or bleeding, dark urine, or yellowing of the skin or eyes.
Common side effects may include:
- stomach pain, loss of appetite;
- nausea, vomiting, diarrhea;
- feeling tired; or
- weight loss.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeZykadia(Oral)if I’m pregnant or breastfeeding?
You should not breast-feed while using this medicine and for at least 2 weeks after your last dose.
Interactions
What drugs and food should I avoid while takingZykadia(Oral)?
Grapefruit may interact with ceritinib and lead to unwanted side effects.Avoid the use of grapefruit products.
Dosage Guidelines & Tips
How to takeZykadia(Oral)?
UseZykadia(Oral)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Ceritinib is usually taken once per day with food.Follow your doctor's dosing instructions very carefully.
If you vomit shortly after taking ceritinib, do not take another dose. Wait until your next scheduled dose time to take the medicine again.
You may be given medication to prevent nausea or vomiting while you are receiving ceritinib.
You may need frequent medical tests to be sure this medicine is not causing harmful effects. Your cancer treatments may be delayed based on the results.
Ceritinib通常是给定的,直到你的身体不长er responds to the medication.
Store at room temperature away from moisture and heat.
Use the medicine as soon as you can, but skip the missed dose if your next dose is due in less than 12 hours.Do notuse two doses at one time.
Overdose Signs
What happens if I overdose onZykadia(Oral)?
Images
LDK 150 MG, NVR
Color: blue/white
Shape: capsule
Imprint: LDK 150 MG, NVR
NVR, ZY1
Color: blue
Shape: round
Form: film coated
Imprint: NVR, ZY1