actemra actpen（皮下）
actemra actpen（皮下）
使用哄骗托克里替in adults治疗：
- 在使用至少一种其他药物后，中度至重度类风湿性关节炎并没有工作;
- giant cell arteritis, (inflammation in the lining of the blood vessels that carry blood from your heart to other parts of your body); and
- 缓慢肺功能与间质肺病引起的肺功能下降。
使用哄骗托克里替in adults and children 2 years and older治疗：
- polyarticular or systemic juvenile idiopathic arthritis ("Still disease"); and
- severe cytokine release syndrome (CRS, an overactive immune response to certain blood cell treatments for cancer).
还正在研究托运毒素用于治疗冠状病毒。美国食品和药品监督管理局（FDA）已授权使用类固醇药物治疗成人和儿童的授权使用与Covid-19住院，并使用补充氧气，呼吸机或Ecmo（一种心肺机器有助于增加血液中的氧气）。
Tocilizumab尚未批准治疗冠状病毒或Covid-19。This medicine is not for use in treating COVID-19 outside of a hospital.
Tocilizumab may also be used for purposes not listed in this medication guide.
uses
什么是actemra actpen（皮下）used for?
- 巨细胞动脉炎
- Rheumatoid Arthritis
- 胶原血管疾病
- Autoimmune Disorder
- Felty的综合征
- Rheumatoid Lung
- Juvenile Idiopathic Arthritis
- Cytokine-Associated Toxicity
warnings
什么是the most important information I should know aboutactemra actpen（皮下）还
如果你对它过敏，你不应该使用托蒂米亚布。
Tell your doctor if you have any signs of infection such as fever, chills, cough, body aches, tiredness, open sores or skin wounds, diarrhea, stomach pain, weight loss, painful urination, or coughing up blood.
如果您已经或暴露于结核病，请告诉您的医生，或者如果你最近旅行了。一些感染在世界某些地区更常见，您可能会在旅行期间暴露。
Tell your doctor if you have ever had:
- 活性或慢性感染;
- 肝脏疾病;
- diverticulitis, ulcers in your stomach or intestines;
- a nerve-muscle disease such as multiple sclerosis;
- 糖尿病;
- HIV, or a weak immune system;
- hepatitis B (or if you are a carrier of the virus);
- 癌症;或者
- 如果您已收到或计划接收任何疫苗。
Using tocilizumab may increase your risk of developing certain types of cancer. Ask your doctor about this risk.
如果您怀孕或母乳喂养，请告诉您的医生。
If you are pregnant:Tell your baby's doctor if you used tocilizumab during pregnancy. This could affect your baby's vaccination schedule during the first months of life. Your name may be listed on a pregnancy registry to track the effects of tocilizumab on the baby.
Side Effects
What are the side effects ofactemra actpen（皮下）还
Get emergency medical help if you have过敏反应的迹象：麻疹;胸痛，呼吸困难，感觉就像你可能会昏倒;你的脸，嘴唇，舌头或喉咙肿胀。
如果你有话，请立即打电话给医生：
- 严重的胃痉挛,腹胀,diarrhea or constipation;
- unusual bleeding--nosebleeds, bleeding gums, abnormal vaginal bleeding, any bleeding that will not stop, blood in your urine or stools, coughing up blood or vomit that looks like coffee grounds;
- liver problems- 食欲，右侧胃痛，呕吐，混乱，暗尿液，粘土凳，黄疸（皮肤或眼睛泛黄）;
- signs of infection--fever, chills, aches, skin sores, diarrhea, burning when you urinate;
- 结核病的迹象: cough, shortness of breath, night sweats, loss of appetite, weight loss, and feeling very tired; or
- 胃或肠道穿孔（孔或撕裂）的迹象- 持续胃痛，肠习惯的变化。
Common side effects may include:
- 流鼻涕或鼻塞，鼻窦疼痛，喉咙痛;
- 头痛;
- 增加血压;
- 异常肝功能试验;或者
- 给出注射的疼痛，肿胀，燃烧或刺激。
这不是一个完整的副作用列表，其他可能会发生。打电话给您的医生，征求有关副作用的医疗建议。您可以在1-800-FDA-1088向FDA报告副作用。
Pregnancy & Breastfeeding
Can I takeactemra actpen（皮下）if I’m pregnant or breastfeeding?
如果您怀孕或母乳喂养，请告诉您的医生。
If you are pregnant:Tell your baby's doctor if you used tocilizumab during pregnancy. This could affect your baby's vaccination schedule during the first months of life. Your name may be listed on a pregnancy registry to track the effects of tocilizumab on the baby.
Interactions
在服用时，我应该避免哪些药物和食物actemra actpen（皮下）还
避免收到“活”疫苗，或者you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).
您仍然可以获得每年流感疫苗或“灭活”或其他疫苗，以预防肝炎，脑膜炎，肺炎，疱疹，HPV或呼吸咳嗽等疾病。在获得任何疫苗之前询问医生。
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
剂量指南和提示
如何服用actemra actpen（皮下）还
Useactemra actpen（皮下）exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
在使用Tocilizumab之前，您的医生可以测试您的结核病或其他感染。
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
对皮肤或静脉注入窥探。这种药通常每1至4周给予每1至4周。对于CRS，通常仅给予一种剂量。
When injected into a vein, this medicine is given slowly for about 1 hour.
Read and follow all Instructions for Use.Ask your doctor or pharmacist if you need help.
只有当您准备好给予它时，才准备注射。Call your pharmacist if the medicine looks cloudy, has changed colors, or has particles in it.
Your healthcare provider will show you where to inject tocilizumab. Do not inject into the same place two times in a row.
不要重复使用针，注射器或自动注射器。将它们放在迹象证明的“Sharps”容器中，并在州或地方法律下处理它。远离儿童和宠物的接触。
您可能更容易发生感染，甚至严重或致命的感染。You will need frequent medical tests.
If you've had hepatitis B, it may come back or get worse.You may need liver function tests while using this medicine and for several months after you stop.
如果您有计划的手术，请告诉您的医生。
按照指示使用所有药物。如果没有医生的建议，请勿改变您的剂量或使用药物使用药物。
将这种药物存放在冰箱的原始纸箱中。保护水分和光线。不要冻结。丢弃在药物标签的到期日之前未使用的任何预填充注射器。
Throw away a prefilled syringe or autoinjector after one use, even if there is still medicine left inside.
Tocilizumab可以对您的身体有持久的影响。在使用此药物后，您可能需要每6个月每6个月使用某些医疗测试。
如果您错过了剂量，请致电您的医生。