Ado-Trastuzumab Emtansine (Intravenous)
Ado-trastuzumab emtansine is used to treat a HER2-positive breast cancer. This medicine is used both for early breast cancer and for breast cancer that has spread to other parts of the body (metastatic).
Ado-trastuzumab emtansine is usually given after other treatments have failed.
kadcyla(ado-trastuzumab) should not be used in place of Herceptin (trastuzumab).
Ado-trastuzumab emtansine也可以用于本药物指南中未列出的目的。
警告
What is the most important information I should know aboutAdo-Trastuzumab Emtansine (Intravenous)?
Tell your doctor if you have ever had:
- 心脏问题;
- 肝病（尤其是乙型肝炎或C）；
- 出血或血液凝血障碍，例如血友病；或者
- 哮喘，慢性阻塞性肺疾病（COPD），睡眠呼吸暂停或其他呼吸障碍。
You may need to have a negative pregnancy test before starting this treatment.
Ado-trastuzumab emtansine可能会伤害未出生的婴儿if the mother or the father is using this medicine.
- If you are a woman,do not use ado-trastuzumab emtansine if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 7 months after your last dose.
- If you are a man,use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 months after your last dose.
- 立即告诉您的医生，当母亲或父亲使用Ado-Trastuzumab Emtansine时，是否发生了怀孕。
Do not breastfeed while using this medicine,至少在您上次剂量后至少7个月。
Side Effects
什么是副作用Ado-Trastuzumab Emtansine (Intravenous)?
如果有紧急医疗帮助signs of an allergic reaction:hives; difficult breathing; swelling of your face, lips, tongue, or throat.
注射过程中可能会发生一些副作用。立即告诉您的护理人员，如果您感到寒冷，头脑昏昏欲睡，发烧或出汗，或者胸部紧绷，心跳快或呼吸困难。
打电话给你的医生啊nce if you have:
- 易于瘀伤，不寻常的出血，紫色或红色斑点；
- coughing up blood or vomit that looks like coffee grounds;
- bloody or tarry stools;
- chest pain, wheezing, dry cough;
- unusual tiredness, feeling light-headed;
- 皮肤苍白，手脚冷；
- numbness, tingling, or burning pain in your hands or feet;
- sudden numbness or weakness (especially on one side of the body), severe headache, slurred speech, balance problems;
- 心脏问题- 在小腿上闲逛，体重快，感觉不到呼吸，咳嗽，快速或敲打心跳，头晕，感觉自己可能昏倒了；
- liver problems--loss of appetite, stomach pain (upper right side), dark urine, jaundice (yellowing of the skin or eyes); or
- signs of tumor cell breakdown--confusion, weakness, muscle cramps, nausea, vomiting, fast or slow heart rate, decreased urination, tingling in your hands and feet or around your mouth.
如果您有某些副作用，您的癌症治疗可能会延迟或永久停止。
Common side effects may include:
- easy bruising or bleeding (especially nosebleeds);
- 恶心，便秘；
- 关节或肌肉疼痛；
- 头痛;或者
- feeling tired.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
怀孕和母乳喂养
Can I takeAdo-Trastuzumab Emtansine (Intravenous)if I’m pregnant or breastfeeding?
You may need to have a negative pregnancy test before starting this treatment.
Do not breastfeed while using this medicine,至少在您上次剂量后至少7个月。
互动
What drugs and food should I avoid while takingAdo-Trastuzumab Emtansine (Intravenous)?
Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
Dosage Guidelines & Tips
How to takeAdo-Trastuzumab Emtansine (Intravenous)?
UseAdo-Trastuzumab Emtansine (Intravenous)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Ado-trastuzumab emtansine is given as an infusion into a vein. A healthcare provider will give you this injection.
该药物必须缓慢地给药，输注可能需要30到90分钟才能完成。
Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when ado-trastuzumab emtansine is injected.
通常每3周给予Ado-Trastuzumab emtansine一次。您的医生将确定治疗多长时间。
您可能需要频繁的医疗检查，以确保这种药物不会引起有害作用。您的癌症治疗可能会根据结果延迟。
如果您错过了Ado-Trastuzumab Emtansine注射的约会，请致电医生以获取指示。
Overdose Signs
What happens if I overdose onAdo-Trastuzumab Emtansine (Intravenous)?
由于这种药物是由医疗保健专业人员在医疗环境中提供的，因此不太可能发生过量。