Alvimopan (Entereg)
Alvimopan reduces certain side effects of opioid medicine used to prevent pain after surgery. Some side effects of opioid medicine (stomach pain, bloating, constipation) can delay recovery after surgery on your stomach or intestines.
Alvimopan will not reduce the pain-relieving effects of the opioid.
Alvimopan is also used to help restore normal digestive functioning after surgery to remove a portion of your intestine.
Alvimopan is available only under a special program, and you will receive only 15 doses. You must be registered in the program and understand the risks and benefits of alvimopan.
Alvimopan may also be used for purposes not listed in this medication guide.
uses
What isAlvimopan (Entereg)used for?
- Gastrointestinal Surgery
warnings
What is the most important information I should know aboutAlvimopan (Entereg)?
You should not use alvimopan if you have severe liver or kidney disease.
Do not take alvimopan if you have used opioid medicine for more than 7 days in a row just before your intestinal surgery。阿片类药物包括可待因、芬太尼、水ocodone, meperidine, methadone, morphine, oxycodone, and many others.
Tell your doctor if you have ever had:
- liver or kidney disease;
- heart disease or prior heart attack;
- blockage in your digestive tract (stomach or intestines);
- a colostomy or ileostomy;
- a pancreas disorder; or
- if you have recently used any type of opioid medicine.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
Side Effects
What are the side effects ofAlvimopan (Entereg)?
Get emergency medical help if you have any of thesesigns of an allergic reaction:hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some people had heart attacks while taking alvimopan long-term. It is not clear whether alvimopan is the actual cause of a heart attack.Call your doctor at once if you have heart attack symptoms,such as:
- chest pain or pressure;
- pain spreading to your jaw or shoulder;
- anxiety, nausea, sweating.
Common side effect may include indigestion.
You may be more likely to have unpleasant effects on your stomach if you used any type of opioid medicine shortly before your surgery.
这不是一个侧eff的完整列表ects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeAlvimopan (Entereg)if I’m pregnant or breastfeeding?
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
Interactions
What drugs and food should I avoid while takingAlvimopan (Entereg)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to takeAlvimopan (Entereg)?
UseAlvimopan (Entereg)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Alvimopan is given only in a hospital for a short period of time.
You will receive your first dose of alvimopan before your surgery. You will then be given additional doses 2 times per day for up to 7 days.
This medicine should not be used for longer than 7 days after your surgery.
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.Do nottake two doses at one time.
Overdose Signs
What happens if I overdose onAlvimopan (Entereg)?
Images
2312
Color: white
Shape: capsule
Imprint: 2312
ADL2698, ADL2698
Color: blue
Shape: capsule
Imprint: ADL2698, ADL2698