Aptivus(Oral)

Aptivus(Oral)

Generic Name: Tipranavir

Tipranavir an antiviral medicine that is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS).Tipranavir is not a cure for HIV or AIDS.

Tipranavir is used together with another drug called ritonavir.

Tipranavir may also be used for purposes not listed in this medication guide.

uses

What isAptivus(Oral)used for?

  • HIV Infection

warnings

What is the most important information I should know aboutAptivus(Oral)?

You should not use tipranavir if you are allergic to it, or if you have:

  • moderate to severe liver disease.

Some medicines can cause unwanted or dangerous effects when used with tipranavir.Your doctor may change your treatment plan if you also use:

  • 一个lfuzosin;
  • cisapride;
  • lurasidone;
  • pimozide;
  • rifampin;
  • sildenafil (Revatio for pulmonary arterial hypertension);
  • St. John's wort;
  • ergot medicine--dihydroergotamine, ergotamine, ergonovine, methylergonovine;
  • heart medication--amiodarone, flecainide, propafenone, quinidine;
  • 一个sedative--oral midazolam, triazolam; or
  • "statin" cholesterol medicine——阿托伐他汀、洛伐他汀,辛伐他汀。

Tell your doctor if you have ever had:

  • liver disease (especially hepatitis B or C);
  • diabetes;
  • high cholesterol or triglycerides;
  • 一个bleeding disorder such as hemophilia; or
  • 一个n allergy to sulfa drugs.

Tell your doctor if you are pregnant, and use your medications properly to control your infection. HIV can be passed to your baby if the virus is not controlled during pregnancy. Your name may be listed on a registry to track any effects of antiviral medicine on the baby.

Tipranavir can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.

Women with HIV or AIDS should not breast feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

Tipranavir should not be given to a child younger than 2 years old.

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Side Effects

What are the side effects ofAptivus(Oral)?

Get emergency medical help if you havesigns of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some people taking tipranavir with ritonavir have developed fatal medical problems including liver damage and bleeding in the brain.Stop taking this medicine and get emergency medical attention if you have:

  • right-sided upper stomach pain, nausea, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
  • unusual bleeding, sudden severe headache, problems with speech or vision.

马上打电话给你的医生如果你有:

  • severe skin rash, blistering, peeling, redness or sunburn;
  • skin rash and also joint or muscle pain, fever, or tightness in your throat; or
  • increased thirst, increased urination, hunger, dry mouth.

Tipranavir affects your immune system, which may cause certain side effects (even weeks or months after you've taken this medicine). Tell your doctor if you have:

  • signs of a new infection--fever, night sweats, swollen glands, cold sores, cough, wheezing, diarrhea, weight loss;
  • trouble speaking or swallowing, problems with balance or eye movement, weakness or prickly feeling; or
  • swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence.

Common side effects may include:

  • nausea, vomiting, diarrhea, stomach pain;
  • skin rash (especially in children);
  • headache, fever, tired feeling; or
  • changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I takeAptivus(Oral)if I’m pregnant or breastfeeding?

C
Risk cannot be ruled out
Based on FDA pregnancy categories

Tell your doctor if you are pregnant, and use your medications properly to control your infection. HIV can be passed to your baby if the virus is not controlled during pregnancy. Your name may be listed on a registry to track any effects of antiviral medicine on the baby.

Tipranavir can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.

Women with HIV or AIDS should not breast feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

Interactions

What drugs and food should I avoid while takingAptivus(Oral)?

If you also take didanosine, take it 2 hours before or after you take tipranavir.

Avoid taking vitamin E supplements if you are using theliquidform of tipranavir.

Using this medicine will not prevent your disease from spreading.Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

Dosage Guidelines & Tips

How to takeAptivus(Oral)?

UseAptivus(Oral)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Tipranavir is taken in combination with ritonavir (Norvir). Use tipranavir and ritonavir regularly to get the most benefit.

Take your medicine with food if you take tipranavirwith ritonavir tablets.

You may take your medicine with or without food if you take tipranavirwith ritonavir capsules or liquid.

Swallow thetipranavir capsulewhole. Do not open or chew it.

Measuretipranavir liquidcarefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Tell your doctor if the child using this medicine has any changes in height or weight. Tipranavir doses are based on body surface area (height and weight) in children, and any changes may affect your dose.

You will need frequent medical tests.

If you need surgery, tell the surgeon ahead of time that you are using tipranavir.

Use all HIV medications as directed and read all medication guides you receive.Do not change your dose or dosing schedule without your doctor's advice.Every person with HIV should remain under the care of a doctor.

Store an unopened bottle of tipranavircapsulesin the refrigerator. Do not freeze.After opening the bottle, store the capsules at room temperature.

Store tipranavirliquid一个t room temperature away from moisture and heat.Do not store the liquid in the refrigerator.

Throw away any capsules or liquid you have not used within 60 days after you first opened the medicine bottle.

What should I do if I missed a dose ofAptivus(Oral)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.Do nottake two doses at one time.

Get your prescription refilled before you run out of medicine completely.

Overdose Signs

What happens if I overdose onAptivus(Oral)?

If you think you or someone else may have overdosed on:Aptivus(Oral), call your doctor or the Poison Control center
(800) 222-1222
If someone collapses or isn't breathing after takingAptivus(Oral),拨打911
911

Images

TPV 250

Color: pink

Shape: capsule

Imprint: TPV 250

Medical Disclaimer

Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health.
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