Aralast NP (Intravenous)
Alpha 1-proteinase inhibitor is a protein (alpha 1-antitrypsin) that occurs naturally in the body and helps prevent breakdown of tissues in the lungs. People who lack this protein because of a genetic deficiency can develop damage to the air sacs in the lungs (emphysema).
Alpha 1-proteinase inhibitor is used to treat alpha 1-antitrypsin deficiency in people with symptoms of emphysema.
Alpha 1-proteinase inhibitor will not cure alpha 1-antitrypsin deficiency,and may not slow the progression of emphysema.
Alpha 1-proteinase inhibitor may also be used for purposes not listed in this medication guide.
uses
What isAralast NP (Intravenous)used for?
- Alpha-1 Proteinase Inhibitor Deficiency
warnings
What is the most important information I should know aboutAralast NP (Intravenous)?
You should not use this medicine if:
- you've had a severe allergic reaction to an alpha 1-proteinase inhibitor; or
- you have an IgA (immunoglobulin A) deficiency or antibody against IgA.
Tell your doctor if you have ever had:
- liver disease; or
- chronic obstructive pulmonary disease (COPD), or other breathing disorder.
Tell your doctor if you are pregnant or breastfeeding.
Not approved for use by anyone younger than 18 years old.
Alpha 1-proteinase inhibitor is made from donated human plasma and may contain viruses or other infectious agents. Donated plasma is tested and treated to reduce the risk of contamination, but there is still a small possibility it could transmit disease. Ask your doctor about any possible risk.
Side Effects
What are the side effects ofAralast NP (Intravenous)?
Get emergency medical help if you havesigns of an allergic reaction: hives, rash; confusion, feeling light-headed; fast heartbeats, chest tightness, difficult breathing; swelling of your face, lips, tongue, or throat.
Your doctor may also prescribe epinephrine (Epi-Pen) to keep with you in case you ever have an allergic reaction to alpha 1-proteinase inhibitor.
Stop using alpha 1-proteinase inhibitor and call your doctor at once if you have:
- wheezing, chest pain, trouble breathing;
- dizziness, severe headache;
- a seizure; or
- sudden numbness or weakness, slurred speech, problems with vision or balance.
You may feel faint during the injection.You may need to rest for a short time afterward.
Common side effects may include:
- cold symptoms such as runny or stuffy nose, sneezing, cough, sore throat;
- headache;
- muscle or joint pain;
- weakness;
- flushing (sudden warmth, redness, or tingly feeling);
- nausea; or
- bruising or bleeding where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeAralast NP (Intravenous)if I’m pregnant or breastfeeding?
Tell your doctor if you are pregnant or breastfeeding.
Interactions
What drugs and food should I avoid while takingAralast NP (Intravenous)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to takeAralast NP (Intravenous)?
UseAralast NP (Intravenous)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Alpha 1-proteinase inhibitor is injected into a vein, usually once per week.
Your first dose may be given in a medical setting where any serious side effects can be quickly treated.
Ask your doctor or pharmacist if you don't understand how to use an injection.
Be sure you understand how to properly mix the powder form of alpha 1-proteinase inhibitor with a liquid (diluent) and how to store the mixture.
Glassiais a liquid form of alpha 1-proteinase inhibitor that is not mixed with a diluent.
Prepare an injection only when you are ready to give it.Call your pharmacist if the medicine looks cloudy, has changed colors, or has particles in it.
Do not reuse a needle or syringe. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.
Doses are based on weight. Your dose may change if you gain or lose weight.
商店Aralast, Prolastin,orZemairaat cool room temperature, away from moisture and heat. Use within 3 hours after mixing.
商店Glassiain the original carton in the refrigerator. Take the medicine out of the refrigerator and let it reach room temperature before preparing your dose.
OnceGlassiahas reached room temperature, you must use it within 1 month.Do not return it to a refrigerator.
不冻结α1-proteinase抑制剂,做什么not use it past the expiration date on the medicine label.
Throw away a vial (bottle) after one use, even if there is still medicine left inside.
Call your doctor for instructions if you miss a dose.