cafetrate（直肠）
Caffeine is a stimulant that causes narrowing of blood vessels (vasoconstriction). Ergotamine is an ergot alkaloid (ER-got AL-ka-loid) that works by narrowing blood vessels around the brain.
咖啡因和ergotamine是用于治疗或预防偏头痛类型头痛的组合药物。
This medication只会对待a headache that has already begun. Itwill not preventmigraine headaches or reduce the number of attacks.
Caffeine and ergotamine should not be used to treat common tension headaches or any headache that seems to be different from your usual migraine headaches.
Caffeine and ergotamine may also be used for purposes not listed in this medication guide.
警告
什么是我应该了解的最重要信息cafetrate（直肠）?
You should not use this medicine if you are allergic to caffeine or ergotamine, or if you have:
- coronary heart disease;
- high blood pressure;
- 血液循环问题;
- sepsis (a severe reaction to an infection);
- liver disease;
- 肾脏疾病;要么
- 如果你怀孕或者可能会怀孕。
Many drugs can cause a dangerous decrease in blood flow when used with caffeine and ergotamine.对脑部的血流和身体其他部位的严重降低可能导致危险的副作用。一些药物不应与咖啡因和ergotamine一起使用。如果您也使用，您的医生可能会改变治疗计划：
- 齐莱顿;
- an antidepressant--fluoxetine, fluvoxamine, nefazodone;
- 抗生素- 甘油霉素，红霉素，甲硝唑，汽霉素;
- antifungal medicine- Clotraimazole，氟康唑，伊丙奈唑，酮康唑;要么
- antiviral medicine to treat HIV/AIDS- 印度纳维尔，Nelfinavir，Ritonavir，Saquinavir。
Do not use caffeine and ergotamine if you are pregnant.它可能会伤害未出生的婴儿或引起出生缺陷。使用有效的避孕药来防止在使用这种药物的同时防止怀孕，如果您怀孕，请告诉您的医生。
使用这种药时，你不应该母乳喂养。
Side Effects
什么是副作用cafetrate（直肠）?
如果有的话，获得紧急医疗帮助signs of an allergic reaction:hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using caffeine and ergotamine and call your doctor at once if you have:
- 你的胃或背部剧烈疼痛;
- bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
- 痉挛或腿部，腿部疼痛或肿胀;
- weak pulses in your arms and legs, numbness and tingling or pain in your hands or feet, blue-colored fingers or toes;
- muscle pain or weakness in your arms or legs;
- fast or slow heart rate;
- 严重的头痛，视力模糊，颈部或耳朵冲击;
- 突然麻木或弱点（特别是在身体的一侧），突然严重的头痛，剧烈讲话，愿景问题或平衡;要么
- 使用直肠栓剂后，在你的直肠上疼痛的疮。
过度使用咖啡因和ergotamine的严重副作用更有可能。This medicine is not for daily use.
常见的副作用可能包括：
- 麻木，刺痛，灼痛;
- 头晕，旋转轰动;
- 弱点;
- itching or swelling;
- nausea, vomiting; or
- （用栓剂使用）直肠疼痛或溃疡。
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
怀孕和母乳喂养
我能拿吗cafetrate（直肠）如果我怀孕或母乳喂养？
Do not use caffeine and ergotamine if you are pregnant.它可能会伤害未出生的婴儿或引起出生缺陷。使用有效的避孕药来防止在使用这种药物的同时防止怀孕，如果您怀孕，请告诉您的医生。
使用这种药时，你不应该母乳喂养。
互动
What drugs and food should I avoid while takingcafetrate（直肠）?
在使用另一种偏头痛头痛医学之前或之后，不要在24小时内使用咖啡因和ergotamine，包含：
[对象对象]，[对象对象]
葡萄柚和葡萄柚汁可以与咖啡因和麦丹胺相互作用，并导致不需要的副作用。Avoid the use of grapefruit products while taking caffeine and ergotamine.
Dosage Guidelines & Tips
How to takecafetrate（直肠）?
采用cafetrate（直肠）完全按照标签的指示，或者由您的医生规定。不要使用较大或更小的量或比推荐更长。
Follow all directions on your prescription label.Never use more than your recommended dose.Overuse of migraine headache medicine can make headaches worse. Tell your doctor if the medicine seems to stop working as well in treating your migraine attacks. This medicine is not for daily use.
To use caffeine and ergotamine tablets:
- 一旦出现头痛症状，或者在攻击已经开始后，就患2片咖啡因和麦红胺。
- 如果你的头痛没有完全消失，你可能会在至少30分钟后获得更多的平板电脑。
- If additional medication is needed, you may take 1 tablet every 30 minutes up to a total of 6 tablets for one migraine attack.
如果您仍有6片患者仍有偏头痛症状，请致电您的医生。Do not take more than a total of 6 tablets in any 24-hour period.Do not take more than a total of 10 tablets over a period of 7 days.
不要服用rectal suppositoryby mouth. It is for use only in your rectum.
Wash your hands before and after inserting the suppository.
使用咖啡因和麦丹胺直肠栓剂：
- Insert 1 suppository at the first sign of migraine headache symptoms, or after an attack has already begun.
- 在插入栓剂之前卸下包装物。避免处理栓剂太长或者它会融化。
- Lie on your back with your knees up toward your chest. Gently insert the suppository into your rectum about 1 inch, pointed tip first.
- Stay lying down for a few minutes while the suppository melts. You should feel little or no discomfort. Avoid using the bathroom for at least an hour.
- If your headache does not completely go away, use 1 more suppository after at least 1 hour has passed.
如果使用共2个直肠栓剂后仍有偏头痛症状，请致电您的医生。每头疼不使用超过2个栓剂。在7天内不要使用超过5个栓剂。
与程序不分享这种药物er person，即使它们具有相同的症状。
Store片剂at room temperature away from moisture, heat, and light.
Store直肠栓剂在冰箱里，不要冻结。
Since caffeine and ergotamine is used only when needed, you are not likely to miss a dose.
每天不服用超过6个咖啡因和奥替胺片或每周超过10片。
不要每周使用超过2个栓剂或每周5个栓剂。
Overdose Signs
What happens if I overdose oncafetrate（直肠）?
过量症状可能包括呕吐，模糊的视觉，在颈部或耳朵中冲击，感觉昏昏欲睡或眩晕，癫痫发作，或在手臂或腿部减少血流的迹象（疼痛，麻木，刺痛，弱脉冲或蓝色外观）。