Isavuconazonium(Intravenous,Oral)
Isavuconazonium is used to treat infections caused by certain types of fungus (aspergillosis or mucormycosis).
Isavuconazonium may also be used for purposes not listed in this medication guide.
uses
What isIsavuconazonium(Intravenous,Oral)used for?
- Aspergillosis -- Invasive
- Mucormycosis -- Invasive
warnings
What is the most important information I should know aboutIsavuconazonium(Intravenous,Oral)?
You should not use isavuconazonium if you are allergic to it, or if you have:
- a genetic heart rhythm disorder called short QT syndrome.
Many drugs can interact and cause dangerous effects. Some drugs should not be used together with isavuconazonium.Your doctor may change your treatment plan if you also use:
- carbamazepine;
- ketoconazole;
- phenobarbital;
- rifampin;
- ritonavir (at high doses); or
- St. John's wort.
Tell your doctor if you have ever had:
- liver disease;
- a heart rhythm disorder; or
- history of an allergic reaction to antifungal medicine, such as fluconazole, itraconazole, ketoconazole, posaconazole, or voriconazole.
Isavuconazonium may harm an unborn baby.Use effective birth control to prevent pregnancy while you are using this medicine and for at least 28 days after your last dose. Tell your doctor if you become pregnant.
你不应该在使用isavuconazon母乳喂养ium.
Isavuconazonium is not approved for use by anyone younger than 18 years old.
Side Effects
What are the side effects ofIsavuconazonium(Intravenous,Oral)?
Get emergency medical help if you havesigns of an allergic reaction(hives, difficult breathing, swelling in your face or throat)or a severe skin reaction(fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Some side effects may occur during the injection. Tell your caregiver right away if you feel dizzy, light-headed, difficult breathing, chilled, or have any numbness, tingling, or changes in your sense of touch.
马上打电话给你的医生如果你有:
- liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
- low potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.
Common side effects may include:
- nausea, vomiting, diarrhea, constipation;
- swelling in your arms or legs;
- headache, back pain;
- cough, shortness of breath;
- low potassium; or
- abnormal liver function tests.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeIsavuconazonium(Intravenous,Oral)if I’m pregnant or breastfeeding?
Isavuconazonium may harm an unborn baby.Use effective birth control to prevent pregnancy while you are using this medicine and for at least 28 days after your last dose. Tell your doctor if you become pregnant.
你不应该在使用isavuconazon母乳喂养ium.
Interactions
What drugs and food should I avoid while takingIsavuconazonium(Intravenous,Oral)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to takeIsavuconazonium(Intravenous,Oral)?
UseIsavuconazonium(Intravenous,Oral)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Isavuconazoniumoralis taken by mouth. Isavuconazoniuminjectionis given as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.
You may take the isavuconazoniumcapsulewith or without food. Swallow thecapsulewhole and do not crush, chew, break, or open it.
Isavuconazoniuminjectionmust be mixed with a liquid (diluent) and then further diluted in an IV bag before using it.Read and carefully follow any Instructions for Use provided with your medicine.Ask your doctor or pharmacist if you do not understand these instructions.
Prepare an injection only when you are ready to give it.Do not use if the medicine has changed colors or has particles in it.Call your pharmacist for new medicine.
You will need frequent blood tests to check your liver function.
Do not stop using isavuconazonium unless your doctor tells you to.
Store thecapsulesin their original blister pack at room temperature, away from moisture and heat.Do not put the capsules into a daily pill box or pill organizer.
Store unusedvialsin a refrigerator.After mixing the diluent into a vial, keep the vial at room temperature and further dilute the mixture in an IV bag within 1 hour.After mixing the final solution, keep the IV bag at room temperature and use it within 6 hours or store the bag in a refrigerator and use it within 24 hours.Do not freeze.
Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.
Call your doctor for instructions if you miss a dose.
Overdose Signs
What happens if I overdose onIsavuconazonium(Intravenous,Oral)?
Overdose symptoms may include dizziness, drowsiness, hot flashes, headache, joint pain, anxiety, feeling restless, numbness or tingling, trouble concentrating, dry mouth, altered sense of taste, numbness in or around your mouth, diarrhea, vomiting, and fast or pounding heartbeats.
Images
766
Color: orange/white
Shape: capsule
Imprint: 766
LOGO, ISA
Color: red/white
Shape: capsule
Imprint: LOGO, ISA