Orinase(Oral)

Orinase(Oral)

Generic Name: Tolbutamide
This drug is obsolete.

Tolbutamide is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.Tolbutamide is not for treating type 1 diabetes.

Tolbutamide may also be used for purposes not listed in this medication guide.

uses

What isOrinase(Oral)used for?

  • Diabetes Type 2
  • Diabetes Mellitus
  • Diabetic Coma (in DM Type II)
  • Diabetic Ketoacidosis (in DM Type II)

warnings

What is the most important information I should know aboutOrinase(Oral)?

You should not use this medicine if you are allergic to tolbutamide, or if have diabetic ketoacidosis (call your doctor for treatment).

Tell your doctor if you have ever had:

  • heart disease;
  • liver or kidney disease;
  • an adrenal or pituitary gland disorder; or
  • a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency.

Before taking tolbutamide, tell your doctor if you have taken another oral diabetes medicine or used insulin during the past 2 weeks.

Tolbutamide may increase your risk of serious heart problems,but not treating your diabetes can also damage your heart and other organs. Talk to your doctor about the risks and benefits of this medicine.

Follow your doctor's instructions about using this medicineif you are pregnant or you become pregnant.Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby. However, you may need to stop taking tolbutamide for a short time just before your due date.

You should not breastfeed while using tolbutamide.

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Side Effects

What are the side effects ofOrinase(Oral)?

Get emergency medical help if you havesigns of an allergic reaction(hives, difficult breathing, swelling in your face or throat)or a severe skin reaction(发烧、喉咙痛、燃烧你的眼睛,皮肤pain, red or purple skin rash that spreads and causes blistering and peeling).

马上打电话给你的医生如果你有:

  • dark urine, jaundice (yellowing of the skin or eyes);
  • severe skin rash, redness, or itching;
  • pale skin, easy bruising or bleeding;
  • fever, chills, sore throat, mouth sores; or
  • low levels of sodium in the body--headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady.

Older adults may be more likely to have low blood sugar while taking this medicine.

Common side effects may include:

  • nausea;
  • heartburn; or
  • full feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I takeOrinase(Oral)if I’m pregnant or breastfeeding?

C
Risk cannot be ruled out
Based on FDA pregnancy categories

Follow your doctor's instructions about using this medicineif you are pregnant or you become pregnant.Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby. However, you may need to stop taking tolbutamide for a short time just before your due date.

You should not breastfeed while using tolbutamide.

Interactions

What drugs and food should I avoid while takingOrinase(Oral)?

Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.

Tolbutamide could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Dosage Guidelines & Tips

How to takeOrinase(Oral)?

UseOrinase(Oral)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office.

Low blood sugar(hypoglycemia)can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, irritability, dizziness, nausea, and feeling shaky. To quickly treat low blood sugar, always keep a fast-acting source of sugar with you such as fruit juice, hard candy, crackers, raisins, or non-diet soda.

Your doctor can prescribe a glucagon emergency injection kit to use in case you have severe hypoglycemia and cannot eat or drink. Be sure your family and close friends know how to give you this injection in an emergency.

Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals.Ask your doctor before changing your dose or medication schedule.

Tolbutamide is only part of a complete treatment program that may also include diet, exercise, weight control, regular blood sugar testing, and special medical care. Follow your doctor's instructions very closely.

Store at room temperature away from moisture, heat, and light.

What should I do if I missed a dose ofOrinase(Oral)?

Take your dose as soon as you can, but skip the missed dose if it is almost time for your next dose.Do notuse two doses at one time.

Overdose Signs

What happens if I overdose onOrinase(Oral)?

Symptoms of severe hypoglycemia include extreme weakness, nausea, tremors, sweating, confusion, trouble speaking, fast heartbeats, or seizure.

If you think you or someone else may have overdosed on:Orinase(Oral), call your doctor or the Poison Control center
(800) 222-1222
If someone collapses or isn't breathing after takingOrinase(Oral),拨打911
911

Images

M 13

Color: white

Shape: round

Imprint: M 13

Medical Disclaimer

Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health.
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