Ribociclib (Kisqali (200 Mg Daily Dose))

Ribociclib is used to treat hormone-related breast cancer in women. Ribociclib is used only if your cancer tests negative for a protein called human epidermal growth factor receptor 2 (HER2). HER2 protein can speed the growth of cancer cells.

Ribociclib is used when the cancer has progressed or has spread to other parts of the body after other treatments.

Ribociclib is given in combination with another cancer medicine such as letrozole (Femara) or fulvestrant (Faslodex).

Ribociclib may also be used for purposes not listed in this medication guide.

uses

What isRibociclib (Kisqali (200 Mg Daily Dose))used for?

  • Breast Cancer
  • Breast Cancer -- Male
  • Neoplasia -- Estrogen Dependent

warnings

What is the most important information I should know aboutRibociclib (Kisqali (200 Mg Daily Dose))?

You should not use ribociclib if you are allergic to it, or if you also take tamoxifen.

Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using ribociclib.

Tell your doctor if you have ever had:

  • slow heartbeats;
  • heart disease or prior heart attack;
  • long QT syndrome;
  • an electrolyte imbalance (such as low levels of calcium, magnesium, phosphorus, or potassium in your blood);
  • liver disease;
  • kidney disease; or
  • signs of infection (fever, chills).

Tell your doctor whether or not you have gone through menopause.

你可能需要有一个消极的怀孕测试性能试验ore starting this treatment.

Do not use ribociclib if you are pregnant.It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 weeks after your last dose.

This medicine may affect fertility (ability to have children)in men.Talk with your doctor if you have concerns about this risk.

You should not breastfeed while using this medicine and for at least 3 weeks after your last dose.

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Side Effects

What are the side effects ofRibociclib (Kisqali (200 Mg Daily Dose))?

Get emergency medical help if you havesigns of an allergic reaction(hives, difficult breathing, swelling in your face or throat)or a severe skin reaction(fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body.Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

马上打电话给你的医生如果你有:

  • fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);
  • low white blood cell counts--fever, mouth sores, skin sores, sore throat, cough, trouble breathing;
  • signs of inflammation in the lungs--new or worsening cough, painful or difficult breathing, wheezing, feeling short of breath even while resting; or
  • liver problems--loss of appetite, upper stomach pain, tiredness, easy bruising or bleeding, dark urine, jaundice (yellowing of the skin or eyes).

Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.

Common side effects may include:

  • low white blood cells, infections;
  • cough;
  • nausea, vomiting;
  • diarrhea, constipation;
  • feeling tired;
  • rash;
  • headache; or
  • hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I takeRibociclib (Kisqali (200 Mg Daily Dose))if I’m pregnant or breastfeeding?

你可能需要有一个消极的怀孕测试性能试验ore starting this treatment.

Do not use ribociclib if you are pregnant.It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 weeks after your last dose.

You should not breastfeed while using this medicine and for at least 3 weeks after your last dose.

Interactions

What drugs and food should I avoid while takingRibociclib (Kisqali (200 Mg Daily Dose))?

Grapefruit may interact with ribociclib and lead to unwanted side effects.Avoid the use of grapefruit products.

Avoid taking an herbal supplement containing St. John's wort at the same time you are taking ribociclib.

Dosage Guidelines & Tips

How to takeRibociclib (Kisqali (200 Mg Daily Dose))?

UseRibociclib (Kisqali (200 Mg Daily Dose))exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Ribociclib is given in a 28-day treatment cycle. You will take the medicine for the first 21 days of each cycle, followed by 7 days off. Your doctor will determine how long to treat you with ribociclib.

Swallow the tablet whole and do not crush, chew, or break it.

Take the medicine at the same time each morning, with or without food.

If you vomit after taking the medicine, wait until the next day to take your next dose.

Do not use a broken or damaged pill.

You may need frequent medical tests to be sure ribociclib is not causing harmful effects. Your cancer treatments may be delayed based on the results.

Store ribociclib in the original container at room temperature, away from moisture and heat.

What should I do if I missed a dose ofRibociclib (Kisqali (200 Mg Daily Dose))?

Skip the missed dose. Take your next dose at the regular time and stay on your once-daily schedule.Do notuse 2 doses in one day.

Overdose Signs

What happens if I overdose onRibociclib (Kisqali (200 Mg Daily Dose))?

If you think you or someone else may have overdosed on:Ribociclib (Kisqali (200 Mg Daily Dose)), call your doctor or the Poison Control center
(800) 222-1222
If someone collapses or isn't breathing after takingRibociclib (Kisqali (200 Mg Daily Dose)),拨打911
911

Images

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RIC, NVR

Color: purple

Shape: round

Form: film coated

Imprint: RIC, NVR

Medical Disclaimer

Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health.
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