Zamicet(Oral)
Acetaminophen and hydrocodone is a combination medicine used to relieve moderate to severe pain.
Acetaminophen and hydrocodone contains an opioid medicine, and may be habit-forming.
Acetaminophen and hydrocodone may also be used for purposes not listed in this medication guide.
uses
What isZamicet(Oral)used for?
- Pain
warnings
What is the most important information I should know aboutZamicet(Oral)?
You should not use this medicine if you are allergic to acetaminophen or hydrocodone, or if you have:
- severe asthma or breathing problems; or
- a blockage in your stomach or intestines.
Tell your doctor if you have ever had:
- breathing problems, sleep apnea (breathing stops during sleep);
- liver disease;
- a drug or alcohol addiction;
- kidney disease;
- a head injury or seizures;
- urination problems; or
- problems with your thyroid, pancreas, or gallbladder.
If you use opioid medicine while you are pregnant, your baby could become dependent on the drug.This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on opioids may need medical treatment for several weeks.
Ask a doctor before using opioid medicine if you are breastfeeding.Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.
Side Effects
What are the side effects ofZamicet(Oral)?
Get emergency medical help if you havesigns of an allergic reaction:hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Opioid medicine can slow or stop your breathing, and death may occur.A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.
In rare cases, acetaminophen may cause a severe skin reaction that can be fatal.This could occur even if you have taken acetaminophen in the past and had no reaction.Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.
马上打电话给你的医生如果你有:
- noisy breathing, sighing, shallow breathing, breathing that stops;
- a light-headed feeling, like you might pass out;
- liver problems--nausea, upper stomach pain, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- low cortisol levels-- nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness; o
- high levels of serotonin in the body--agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, diarrhea.
Serious breathing problems may be more likely in older adults and in those who are debilitated or have wasting syndrome or chronic breathing disorders.
Common side effects include:
- dizziness, drowsiness, feeling tired;
- nausea, vomiting, stomach pain;
- constipation; or
- headache.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeZamicet(Oral)if I’m pregnant or breastfeeding?
If you use opioid medicine while you are pregnant, your baby could become dependent on the drug.This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on opioids may need medical treatment for several weeks.
Ask a doctor before using opioid medicine if you are breastfeeding.Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.
Interactions
What drugs and food should I avoid while takingZamicet(Oral)?
Avoid driving or operating machinery until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.
Do not drink alcohol.Dangerous side effects or death could occur.
Ask a doctor or pharmacist before using any other medicine that may contain acetaminophen (sometimes abbreviated as APAP).Taking certain medications together can lead to a fatal overdose.
Dosage Guidelines & Tips
How to takeZamicet(Oral)?
UseZamicet(Oral)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label.Never take this medicine in larger amounts, or for longer than prescribed. An overdose can damage your liver or cause death.Tell your doctor if you feel an increased urge to use more of this medicine.
Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH.Keep the medicine in a place where others cannot get to it. Selling or giving away this medicine is against the law.
Measureliquid medicinecarefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
If you need surgery or medical tests, tell the doctor ahead of time that you are using this medicine.
You should not stop using this medicine suddenly.Follow your doctor's instructions about tapering your dose.
Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.
Do not keep leftover opioid medication.Just one dose can cause death in someone using this medicine accidentally or improperly.Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, flush the unused medicine down the toilet.
Since this medicine is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next dose.Do notuse two doses at one time.
Overdose Signs
What happens if I overdose onZamicet(Oral)?
Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.
Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.