Zepzelca(Intravenous)
Lurbinectedin is used to treat small cell lung cancer that has spread to other parts of the body (metastatic).
Lurbinectedin is given after a platinum cancer medicine did not work or has stopped working.
Lurbinectedin也可能用于不是李sted in this medication guide.
uses
What isZepzelca(Intravenous)used for?
- Small Cell Lung Cancer
warnings
What is the most important information I should know aboutZepzelca(Intravenous)?
Tell your doctor if you have ever had:
- liver or kidney disease;
You may need to have a negative pregnancy test before starting this treatment.
Lurbinectedin can harm an unborn baby我f the mother or the father is using this medicine.
- If you are a woman,do not use lurbinectedin if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.
- If you are a man,use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 months after your last dose.
- Tell your doctor right away if a pregnancy occurs while either the mother or the father is using lurbinectedin.
Do not breastfeed while using this medicine,and for at least 2 weeks after your last dose.
Side Effects
What are the side effects ofZepzelca(Intravenous)?
Get emergency medical help if you havesigns of an allergic reaction:hives; difficult breathing; swelling of your face, lips, tongue, or throat.
马上打电话给你的医生如果你有:
- easy bruising, unusual bleeding, purple or red spots under your skin;
- low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet;
- low white blood cell counts--fever, mouth sores, skin sores, sore throat, cough, trouble breathing;
- signs of sepsis--confusion, fever or chills, severe drowsiness, fast heartbeats, rapid breathing, feeling very ill; or
- liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Common side effects may include:
- low blood cell counts;
- cough, trouble breathing;
- nausea, vomiting, loss of appetite;
- 我ncreased thirst or urination;
- diarrhea, constipation;
- muscle or joint pain;
- feeling tired; or
- abnormal blood tests.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeZepzelca(Intravenous)我f I’m pregnant or breastfeeding?
You may need to have a negative pregnancy test before starting this treatment.
Do not breastfeed while using this medicine,and for at least 2 weeks after your last dose.
Interactions
What drugs and food should I avoid while takingZepzelca(Intravenous)?
Grapefruit may interact with lurbinectedin and lead to unwanted side effects.Avoid the use of grapefruit products.
Dosage Guidelines & Tips
How to takeZepzelca(Intravenous)?
UseZepzelca(Intravenous)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Before you receive a dose of lurbinectedin, you may need a blood test to check your liver function.
Lurbinectedin is given as an infusion into a vein. A healthcare provider will give you this injection.
This medicine must be given slowly, and the infusion can take at least 1 hour to complete.
You may be given infusions of other medications to help prevent nausea and vomiting.
Lurbinectedin is usually given once every 21 days.
Lurbinectedin can lower your blood cell counts.Your blood will need to be tested often.Your cancer treatments may be delayed based on the results.
Your doctor will determine how long to treat with you with this medicine.
Call your doctor for instructions if you miss an appointment for your lurbinectedin injection.
Overdose Signs
What happens if I overdose onZepzelca(Intravenous)?
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.