Zolgensma (8.1-8.5 Kg)(Intravenous)
Zolgensma (8.1-8.5 Kg)(Intravenous)
Onasemnogene abeparvovec is used to treat spinal muscular atrophy in children younger than 2 years old who have a specific gene mutation that affects nerve signals to the muscles.
This medicine may not be effective in a child who is completely paralyzed or is dependent on a ventilator for breathing.
Onasemnogene abeparvovec may also be used for purposes not listed in this medication guide.
uses
What isZolgensma (8.1-8.5 Kg)(Intravenous)used for?
- Spinal Muscular Atrophy
warnings
What is the most important information I should know aboutZolgensma (8.1-8.5 Kg)(Intravenous)?
This medicine can cause serious liver damage.Tell your doctor if your child has ever had liver problems.
It may not be safe to breastfeed your child while he or she is receiving this medicine. Ask your doctor about any risk.
Side Effects
What are the side effects ofZolgensma (8.1-8.5 Kg)(Intravenous)?
Get emergency medical help if your child hassigns of an allergic reaction:hives; difficult breathing; swelling of the face, lips, tongue, or throat.
Call your doctor at once if your child has:
- jaundice (yellowing of the skin or eyes); or
- easy bruising, unusual bleeding, purple or red spots under your skin.
Common side effects may include:
- vomiting; or
- abnormal liver function tests.
这不是一个侧eff的完整列表ects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I takeZolgensma (8.1-8.5 Kg)(Intravenous)if I’m pregnant or breastfeeding?
It may not be safe to breastfeed your child while he or she is receiving this medicine. Ask your doctor about any risk.
Interactions
What drugs and food should I avoid while takingZolgensma (8.1-8.5 Kg)(Intravenous)?
If your child is also taking steroid medicine, the child should not receive certain vaccines.If your child is due for any vaccine, ask your doctor first before your child gets the shot(s).
Onasemnogene abeparvovec can pass into your child's stools (bowel movements). For at least 1 month after your child receives a dose, avoid allowing the child's stools to come into contact with hands or other surfaces. Wear rubber gloves while cleaning up the child's body fluids, handling contaminated trash or laundry, or changing diapers. Seal used diapers in disposable bags and throw them into the trash. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.
Dosage Guidelines & Tips
How to takeZolgensma (8.1-8.5 Kg)(Intravenous)?
UseZolgensma (8.1-8.5 Kg)(Intravenous)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Your doctor will perform blood tests to make sure your child does not have conditions that would make it unsafe to receive onasemnogene abeparvovec.
Onasemnogene abeparvovec is given as an infusion into a vein, usually only one time. A healthcare provider will give your child this injection.
This medicine must be given slowly, and the infusion can take about 1 hour to complete.
Your child may be given steroid medication to help prevent serious side effects of onasemnogene abeparvovec. Keep giving your child the steroid for as long as your doctor has prescribed. The doctor may gradually reduce the dose as your child continues taking the steroid.
Your child will need frequent blood tests to check his or her liver function.
Your child may need to be vaccinated against respiratory syncytial (sin-SISH-ul) virus, or RSV. Follow the doctor's instructions about this vaccination.
If your child vomits shortly after taking the steroid medicine, do not take another dose. Call the doctor for instructions.
Onasemnogene abeparvovec is used as a single dose and does not have a daily dosing schedule.
Overdose Signs
What happens if I overdose onZolgensma (8.1-8.5 Kg)(Intravenous)?
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.