Nucala Prefilled Autoinjector(Subcutaneous)
米epolizumab is a monoclonal antibody that works by reducing levels of eosinophils (a type of white blood cell). High eosinophil levels can contribute to certain disorders.
大甲珠单抗用于预防爆发或减少成人和儿童至少12岁的高嗜酸性粒细胞水平（或HES）的高症状（HERSOSINOMOLOTIC综合征，或HES）。
米epolizumab is also used in adults to help control symptoms and reduce flares of a rare autoimmune disorder called eosinophilic granulomatosis with polyangiitis (EPGA).
巨蛋白单抗还与其他药物一起使用，以帮助控制至少6岁的成年人和儿童的严重哮喘。米epolizumab is not a rescue medicine for asthma attacks.
Mepolizumab也可以用于本药物指南中未列出的目的。
用途
What isNucala Prefilled Autoinjector(Subcutaneous)用于？
- Asthma -- Maintenance
- Wegener's Granulomatosis
警告
我应该知道的最重要的信息是什么Nucala Prefilled Autoinjector(Subcutaneous)?
You should not use mepolizumab if you are allergic to it.
Mepolizumab未获得6岁以下儿童的批准。不应使用mepolizumab来治疗12岁以下的任何人，或者在18岁以下的任何人中EPGA。
Tell your doctor if:
- you also use steroid asthma medication;
- you have a history of parasite infection (such as roundworms or tapeworms); or
- you have a history of herpes zoster (also called shingles).
You may be given a zoster (shingles) vaccine before you start using mepolizumab.
If you also use an oral or inhaled steroid medication, you should not stop using it suddenly.请按照医生的指示进行缩小剂量。
Tell your doctor if you are pregnant.Your name may be listed on a pregnancy registry to track the effects of mepolizumab on the baby.
使用这种药物时母乳喂养可能不安全。向您的医生询问任何风险。
Side Effects
什么是副作用Nucala Prefilled Autoinjector(Subcutaneous)?
如果有紧急医疗帮助signs of an allergic reaction:hives, rash; wheezing, chest tightness, difficult breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat.
马上打电话给你的医生如果你有:
- unusual pain or tiredness;
- 体内任何地方燃烧或刺痛；或者
- a red or blistering skin rash.
常见的副作用可能包括：
- headache;
- feeling tired;
- 背痛;或者
- pain, swelling, redness, burning, or itching where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
怀孕和母乳喂养
Can I takeNucala Prefilled Autoinjector(Subcutaneous)如果我怀孕还是母乳喂养？
Tell your doctor if you are pregnant.Your name may be listed on a pregnancy registry to track the effects of mepolizumab on the baby.
使用这种药物时母乳喂养可能不安全。向您的医生询问任何风险。
互动
What drugs and food should I avoid while takingNucala Prefilled Autoinjector(Subcutaneous)?
遵循医生关于食物，饮料或活动的任何限制的指示。
Dosage Guidelines & Tips
How to takeNucala Prefilled Autoinjector(Subcutaneous)?
采用Nucala Prefilled Autoinjector(Subcutaneous)exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Your doctor may perform blood tests to make sure you do not have conditions that would prevent you from safely using mepolizumab.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
米epolizumab is not a rescue medicine for asthma attacks.采用only fast-acting inhalation medicine for an attack. Seek medical attention if your breathing problems get worse quickly, or if you think your asthma medications are not working as well.
米epolizumab is injected under the skin, usually once every 4 weeks. A healthcare provider may teach you how to properly use the medication by yourself. Follow all directions on your prescription label
甲珠单抗粉末必须与液体（稀释剂）混合，然后再使用。Read and carefully follow any Instructions for Use provided with your medicine.如果您不了解所有指示，询问您的医生或药剂师。
轻轻旋转，但是do not shake the mixed medicine。仅在准备好给它时准备注射。如果药物改变了颜色或中有颗粒，请勿使用。Call your pharmacist for new medicine.
Store thevial (bottle)in its original carton at room temperature. Protect from light and do not freeze.
Store theprefilled syringe或者autoinjector在冰箱中的原始纸箱中。不要冻结或摇动药物。After removing the medicine from the carton, you must use the syringe or autoinjector within 8 hours.
You may store the prefilled syringe or autoinjector in the unopened carton at room temperature for up to 7 days.扔掉从冰箱中放出的注射器或自动注射器超过7天。
Each vial, prefilled syringe, or autoinjector is for one use only. Throw it away after one use, even if there is still medicine left inside.
采用a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.
尽快使用药物，但是如果几乎是时候了下一个剂量的时间，请跳过错过的剂量。不要use two doses at one time.