Isordil Titradose - Side Effects, Interactions, Uses, Dosage, Warnings

Isosorbide dinitrate is a nitrate that dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.

Isosorbide dinitrate is used totreatorpreventattacks of chest pain (angina).

Only the sublingual tablet should be used to treat an angina attack that has already begun.

Isosorbide dinitrateregularandextended-releasetablets are used topreventangina attacksbut will not treatan angina attack.

Isosorbide dinitrate may also be used for purposes not listed in this medication guide.

warnings

What is the most important information I should know aboutIsordil Titradose(Oral)?

You should not use isosorbide dinitrate if:

you are allergic to isosorbide dinitrate, isosorbide mononitrate, or nitroglycerin; or
you have early signs of a heart attack (chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating).

You should not take erectile dysfunction medicine (Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, vardenafil) while you are taking isosorbide dinitrate.Taking these medicines together can cause a sudden and serious decrease in blood pressure.

To make sure isosorbide dinitrate is safe for you, tell your doctor if you have:

congestive heart failure;
kidney disease; or
low blood pressure.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether isosorbide dinitrate passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

Side Effects

What are the side effects ofIsordil Titradose(Oral)?

Get emergency medical help if you havesigns of an allergic reaction:hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

马上打电话给你的医生如果你有:

a light-headed feeling, like you might pass out;
worsening angina pain;
fast or slow heart rate; or
pounding heartbeats or fluttering in your chest.

Isosorbide dinitrate can cause severe headaches. These headaches may gradually become less severe as you continue to use nitroglycerin.Do not stop taking this medicine to avoid headaches.Ask your doctor before using any headache pain medication.

Common side effects may be more likely to occur, such as:

headache; or
flushing (warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I takeIsordil Titradose(Oral)if I’m pregnant or breastfeeding?

Risk cannot be ruled out

Based on FDA pregnancy categories

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether isosorbide dinitrate passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

Interactions

What drugs and food should I avoid while takingIsordil Titradose(Oral)?

This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid drinking alcohol. Alcohol may increase certain side effects of isosorbide dinitrate (dizziness, drowsiness, feeling light-headed, or fainting).

Dosage Guidelines & Tips

How to takeIsordil Titradose(Oral)?

UseIsordil Titradose(Oral)完全按照指示标签,或规定by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Before using isosorbide dinitrate to treat a sudden angina attack, your doctor may want you to first use a nitroglycerin sublingual tablet. Follow your doctor's instructions about what medications to use during an attack and how much time to allow between doses.

Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended.If you use too much isosorbide dinitrate, it might stop working as well in controlling your condition.

Try to rest or stay seated when you take this medicine (may cause dizziness or fainting).

To prevent angina attacks,isosorbide dinitrate is usually taken at regular intervals.

To treat an angina attack that has already begun,use the medicine at the first sign of chest pain. Place the tablet under your tongue and allow it to dissolve slowly. Do not chew or swallow it.

You may use thesublingual tabletwithin 15 minutes before an activity you think might cause chest pain. Follow your doctor's instructions.

Do not crush, chew, break, or open anextended-release capsule or tablet. Swallow it whole.

Follow your doctor's dosing instructions very carefully.If your doctor changes your brand, strength, or type of isosorbide dinitrate, your dosage needs may change. Ask your pharmacist if you have any questions about the new kind of isosorbide dinitrate you receive at the pharmacy.

Seek emergency medical attention if your chest pain gets worse or lasts longer than 5 minutes, especially if you have trouble breathing or feel weak, dizzy, or nauseated, or lightheaded.

You may have very low blood pressure while taking this medicine. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. Prolonged illness can lead to a serious electrolyte imbalance, making it dangerous for you to use isosorbide dinitrate.

If you take isosorbide dinitrate on a regular schedule to prevent angina, do not stop taking it suddenly or you could have a severe attack of angina.Keep this medicine on hand at all times. Get your prescription refilled before you run out of medicine completely.

Store at room temperature, away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

What should I do if I missed a dose ofIsordil Titradose(Oral)?

Since isosorbide dinitrate is sometimes used only when needed, you may not be on a dosing schedule. If you are on a schedule, take the missed dose as soon as you remember. Skip the missed dose if your next dose is less than 2 hours away.

If you are using theextended-release capsule or tabletand your next dose is less than 6 hours away, skip the missed dose and use the medicine at your next regularly scheduled time.

Do notuse extra medicine to make up a missed dose.

Overdose Signs

What happens if I overdose onIsordil Titradose(Oral)?

Overdose symptoms may include a severe throbbing headache, fever, confusion, severe dizziness, fast or pounding heartbeats, vision problems, nausea, vomiting, stomach pain, bloody diarrhea, trouble breathing, sweating, cold or clammy skin, fainting, and seizure (convulsions).

If you think you or someone else may have overdosed on:Isordil Titradose(Oral), call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after takingIsordil Titradose(Oral),拨打911

911

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Isordil Titradose(Oral)

Isordil Titradose(Oral)

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Side Effects

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Pregnancy & Breastfeeding

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Interactions

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