What Are Cold Sores? Symptoms, Causes, Diagnosis, Treatment, and Prevention

Cold sores are small, painful blisters that typically form on or near the lips. These tiny fluid-filled blisters are sometimes called fever blisters or oral herpes, notes the Mayo Clinic. (1)

Cold sores are highly contagious and can spread through saliva or skin contact. It’s a common condition, with some people experiencing their first outbreak during childhood, according to TeensHealth. (2)

There's no cure for cold sores, but the good news is that many cold sores usually go away on their own in a week or two and don’t leave a trace. (1)

To relieve pain and accelerate healing, medications and home remedies can help, says the Mayo Clinic. (3)

Symptoms of cold sores vary, with the first exposure or primary outbreak usually being the most severe, saysAllison Arthur, MD, a board-certified dermatologist based in Orlando, Florida.

According to the American Academy of Dermatology, first-time cold sore symptoms may include: (4)

• Painful blisters on the lips, cheeks, mouth, nose, or throat (which eventually pop and form scabs)
• Gingivostomatitis
• Mouth and throat pain
• Swelling in the neck
• Fever and body aches

You’ll still have painful blisters with recurrent outbreaks, but the more severe symptoms, like body aches and a fever, are less likely to return.

It’s important to note that while cold sores typically form outside of the mouth, these sorescanform inside the mouth during your first outbreak. This is known as acute herpetic gingivostomatitis. (4) For this reason, you might initially mistake a first-time cold sore for a canker sore.Canker soresareulcersthat form on the mucous membranes inside the mouth or on the tongue, per the Mayo Clinic. (5)

A cold sore can develop anytime after you're first infected with a herpes simplex virus (HSV). You may also notice early signs of an outbreak one or two days before a blister appears.

Earlysymptoms of a cold soremay include: (4)

• Pain
• Burning
• Tingling
• Itching

The blister appears within 24 to 48 hours of the first symptom. After a couple of days, the blister will burst and ooze with pus. A scab will then form over the blister. (4)

了解更多关于症状和体征of Cold Sores

Cold Sore vs. Canker Sore: What’s the Difference?

You may mistake a cold sore for a canker sore, but these bumps have key differences, including their:

AppearanceCanker sores are painful red or white bumps that typically form on the gums, inside the lips or cheek, or on the tongue. Unlike cold sores, they don't blister or scab.

Contagiousness与唇疱疹,口腔溃疡不是由herpes and they aren't contagious. So while it is possible to spread a cold sore to someone through kissing or sharing eating utensils, this isn’t the case with a canker sore. (5)

CauseCold sores are commonly caused byHSV-1, and yet thecause of a canker soreis unknown. Factors that may contribute to a canker sore include a family history of canker sores, injury to the mouth, a weak immune system, or avitamin deficiency. (5)

Learn More About the Difference Between Cold Sores and Canker Sores

Cold sores are caused by the herpes simplex virus (HSV). (1)

There are two types of HSV. Most cold sores are caused by type 1 (HSV-1). Type 2 (HSV-2) usually affects the genital area, but it can also cause cold sores around the mouth, says Dr. Arthur. (2)

This can happen after oral sex with someone who hasgenital herpes, or if you kiss someone who has HSV-2 cold sores around their mouth.

Upward of 90 percent of adults have the virus that causes a cold sore, and these individuals are often infected in childhood after being kissed by someone with the virus. (1)

Cold sores can be found on or around the lips, but some people also get sores on the cheek, or around the nose and the eyes. (1)

Once you’re infected with HSV-1, the virus travels to your nerves and stays in your body for life. The virus can lie inactive or dormant, so some people infected with HSV-1 never get a cold sore. In fact, some people don’t even know that they’re infected with the virus because they never have symptoms. (4)

Unfortunately, you can still pass the virus to others even when you don’t have visible symptoms of a cold sore, according to NHS Inform. (6)

Cold sores occur when the virus awakens in the body.

Certain factors can trigger this awakening and cause an outbreak, notes the AAD. (7)

These triggers include:

• A viral infection or fever
• Hormonalchanges
• Stress
• Fatigue
• Exposure to sun and wind
• Changes in the immune system

Sometimes, a cold sore has unknown triggers.

Learn More About Causes of Cold Sores: Common Risk Factors and More

A cold sore is treatable at home, so most people don’t see a doctor. Under certain conditions, however, a severe cold sore may require a visit to your family doctor or a dermatologist. (3)

Doctors can usually diagnose a cold sore by looking at the lesion. More rarely, your doctor may take a fluid sample from the cold sore to see if you have HSV. (3)

Prognosis of Cold Sores

There's no cure for cold sores, nor is there a cure for the virus that causes a cold sore. (1) Once you're infected, the virus stays in your body for life.

But even with recurrence, in healthy individuals the prognosis for a cold sore is typically good and complications are rare, unless you are immunocompromised.

A first-time cold sore typically lasts 10 to 14 days. Later outbreaks might last this long, or they might heal sooner, as soon as within five days. (4)

A number of treatments are helpful for cold sore outbreaks.

Medication Options

因为疱疹病毒引起的,冷杉t line of defense is the over-the-counter antiviralAbreva (docosanol)to help your body fight the virus and reduce the duration of an outbreak. (3) This medication is most effective when taken at the first sign of tingling and itching. (6)

Additionally, use an over-the-counter oral pain reliever, such aslidocaine,benzocaine (Orajel),dibucaine, orbenzyl alcohol, to relieve cold sore pain and inflammation. (3) Apply ointments and creams directly to the cold sore as directed. Other pain relief options include a cool compress, or takeibuprofen (Advil),aspirin, oracetaminophen (Tylenol). (2,3)

If a cold sore doesn’t respond to over-the-counter treatment, ask your doctor about a prescription antiviral to shorten the duration of an outbreak. If you have frequent outbreaks, you may need an antiviral daily to suppress the virus and control symptoms. (8) You can also ask about the topical therapyDenavir (penciclovir), which can be used to shorten the duration of a cold sore outbreak, according to Medline Plus. (9) To use, you typically apply it every two hours while awake, for four days.

Alternative and Complementary Therapies

Other tips to reduce an outbreak include getting plenty of rest, managing stress, and wearingsunscreento protect against strong sun exposure. (7)

Alternative therapies may also relieve a cold sore, though more research is needed. According to a past study, researchers found that a combination of rhubarb and sage had the same healing effect asacyclovir, a topical antiviral commonly used to treat herpes infections. (10)

Additionally, research published in 2018 inIntegrative Medicinefound that 3 percent propolis ointment applied to areas affected by HSV-1 reduced symptoms of infection by three to four days. Propolis is a compound produced by bees. Participants applied the ointment four to five times a day for 10 days. (11)

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Prevention of Cold Sores

Cold sores are highly contagious, but you can protect yourself. Since the virus can spread through close personal contact, it's important that you don't share personal items with anyone — especially during an outbreak, notes the Cleveland Clinic. (12)

Personal items include clothes, makeup, razors, and towels. You should also avoid sharing food and drinks with others.

Keep in mind, too, cold sores can spread to other parts of the body. So if you have an outbreak, avoid touching your cold sore with your hands. After applying creams or ointments over a cold sore, wash your hands immediately with warm soap and water. (1)

If you're prone to cold sores in the summer, sunlight might be a trigger. Wear a moisturizing lip balm with SPF protection to help prevent an outbreak. (7)

See a doctor if you have cold sore complications. This includes a cold sore that spreads to different parts of your body, such as your eyes or fingers. Additionally, see a doctor if you have a weak immune system. (2)

“People who are immunocompromised [have a weakened immune system due toHIVor medications following organ transplantation] can develop severe outbreaks and have frequent episodes of cold sores,” says Arthur.

If your body is unable to fight the virus, it can also spread to your spinal cord and brain. (1) If you haveeczema, there's also the risk of cold sores spreading across your body. (1)

It's estimated that over half of Americans between ages 14 and 49 have the virus that causes cold sores. Many people get the virus in childhood after being kissed by an infected person. (7)

Some people with the virus never have an outbreak, whereas others have frequent outbreaks throughout their life. Fortunately, cold sores occur less often with age. Outbreaks tend to slow down after the age of 35. (7)

Cold sores have been associated with other conditions and health problems. For example, if you have a weakened immune system, certain illnesses might trigger an outbreak. These illnesses include: (12)

• Common cold
• Flu
• Pneumonia
• Urinary tract infection
• Cancer

Skin conditions like eczema andpsoriasisalso put you at risk of an outbreak. And because fluctuating hormone levels can trigger outbreaks, a cold sore might develop while you’re pregnant ormenstruating. (12)

Favorite Resources for Essential Cold Sore Information

American Academy of Dermatology (AAD)

The AAD provides a comprehensive overview of cold sores ranging from symptoms toself-care. There's an information section for parents, as well as information on public health programs. Use the “find a dermatology” tool to locate a doctor in your area.

Cleveland Clinic

This is another helpful tool to find useful information related to cold sores. The Cleveland Clinic doesn’t only offer advice on treatments, but also advice on prevention and living with cold sores. Use the online tool to chat with a representative or schedule an appointment.

For more on connecting with a dermatologist online, check out our article “Why You Shouldn’t Skip Your Dermatology Appointment During COVID-19.”

Mayo Clinic

The Mayo Clinic provides straightforward information about cold sores. The site features general information such as symptoms, treatments, and prevention. You’ll also find guidelines on when to see a doctor, and tips on how to prepare for an appointment.

MedlinePlus

MedlinePlus offers a wealth of resources for cold sores. You’ll find general information for symptoms and treatments, as well as links to clinical trials, journal articles, and patient handouts.

Favorite Online Support Network

Drugs.com

Support groups are an excellent way to get advice and connect with those who understand your condition. Join the Drugs.com support group to ask questions and find the latest information related to oral herpes.