2013年6月3日星期一 -HPV阳性患者的配偶口咽癌症在统计上，统计学上，不适于培养HPV口腔感染的风险增加，因此不太可能发展HPV阳性咽喉癌。来自新研究的新闻可能有助于缓解HPV阳性头部和颈部癌症患者的焦虑，其中一些人通过亲密的活动将HPV传递给合作伙伴。
The finding of the Human Oral Papillomavirus Transmission in Partners over Time study (HOTSPOT) were presented Saturday at the American Society of Clinical Oncology's annual conference. Gypsyamber D'Souza, PhD, an associate professor of epidemiology at Johns Hopkins Bloomberg School of Public Health, began her pilot study several years ago in response to the clinical experience of many oropharyngeal cancer patients.
“他们对HPV传播有很多问题和担忧，”D'Souza博士说。“患者担心的性行为离婚和性行为的变化。”
For the study, D'Souza and her fellow researchers recruited 147 patients with HPV-positive oropharyngeal cancer, along with 83 of their spouses and partners. The majority of patients enrolled in the study were men, while the majority of the spouses were women. The median age for study subjects was 56.
百分之五of the female partners were found to be HPV positive — about the same as would be expected in the general population.
D'Souza's findings are good news to many patients, but she emphasized the need to do a better job educating patients — and the public — on the actualcancer risk由HPV构成。“HPV相关的头部和颈部癌症往往非常耻辱，并且有关于HPV如何传播的误解，”D'Souza说。“有些患者是否有担忧，如果这表明了不忠或高风险伙伴。相反，我们认为它只会看到它只需要一个伴侣，如果你无法清楚，那就太运气了。”
The人乳头状瘤病毒是美国最常见的性传播感染。根据疾病控制的中心，目前约有7900万美国人具有HPV感染，尽管约90％感染病毒的症状没有任何症状或发展癌症。病毒是主要原因宫颈癌但近几十年来，HPV相关的头部和颈部癌症的速率急剧上升，特别是白人。白人人类增加的原因是未知的，但一种可能性是增加口交的率贡献。
Erich Sturgis, a professor in the department of head and neck surgery and the department of epidemiology at MD Anderson Cancer Center, said men may be at higher risk for contracting an oral HPV infection because a woman carries higher levels of HPV once she's infected. "There’s data out there that if you measure the viral load in cervix samples versus penile samples, there's a much higher viral load in the cervix," he said — adding that might mean oral sex is riskier for men.
Sturgis said he wasn't surprised by the study's findings. "It’s basically how we’ve been counseling patients and their spouse for years." He added that some head and neck cancer patients don't know how long ago they may have contracted HPV or even how it may have happened. By the time patient develops cancer, the HPV is unlikely to be communicable, Sturgis explained, which means a partner's risk for an oral HPV infection is low.
