The Risks of Untreated Rheumatoid Arthritis

Left untreated, RA can lead to a host of health problems, so it’s essential to find — and stick with — a treatment plan that works.

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illustration of joint pain
Following your RA treatment not only helps ease symptoms like joint pain and stiffness — it can also prevent progression of the disease. bob体育在线

Staying on top of yourrheumatoid arthritis (RA)treatment might seem like an inconvenience at times, but it’s worth it — in fact, the alternative can put your quality of life at risk.

Without proper treatment, RA can cause long-term damage to joints and serious damage to your whole body, along with persistent pain and disability, saysDavid Pisetsky, MD, PhD, arheumatologistand professor of medicine and immunology at Duke University School of Medicine in Durham, North Carolina. Without proper treatment, over time, your joints may become deformed and lose some of their function.

但在翻盖方面,正确的治疗可以很长,以防止长期损坏和保持关节功能。“随着目前的治疗方案,大多数人可以妥善控制症状并减少RA进展,”Pisetsky博士说。“许多人甚至可以体验缓解。”

Short-Term Complications of Untreated RA

If left untreated, RA can cause a number of short-term complications, particularlyjoint pain, Pisetsky says. And because RA affects the entire body, without treatment you may also experience general malaise, fever, and fatigue.

Untreated RA can also increase the risk for infection, Pisetsky says. RA is an inflammatory type of autoimmune disease — meaning when you have RA, the immune system concentrates on attacking your joints and other tissues instead of protecting you from illness. The more severe your RA, the greater the risk for infection, according to the Arthritis Foundation (AF).

When RA Goes Untreated: Long-Term Health Issues

If RA is left untreated in the long-term, it can affect not just quality of life but the duration of it, too. “Persistent inflammation can lead to a shorter lifespan,” Pisetsky explains.

Uncontrolled RA can also increase your risk for heart disease, because RA-related inflammation not only affects the joints, but also the heart. This inflammation can also contribute to narrowing of your blood vessels, according to the AF, allowing plaque to build up.

People who have RAhave as much as twice the risk of heart disease as the general population,according to the AF. According to study published in April 2018 inBMC Rheumatology, due to the link between RA and heart problems, it's important to manage not just RA butheart disease risk factorssuch as high blood pressure,high cholesterol, smoking, diabetes, and being sedentary.

And the more advanced your RA, the greater your risk for heart damage, the American College of Rheumatology notes.

However, untreated RA can affect more than just your joints and your heart, leading to complications ranging from skin issues, to bone thinning, to eye complications, and beyond.

That said, following a regular treatment plan that helps slow the progression of your RA can help protect your joints, your heart, your overall health and well-being —andyour life.

The Importance of Seeking Early Treatment

About 85 percent of those who develop RA sustain joint damage, and most of that damage occurs within the first two years of onset, according to theJohns Hopkins Arthritis Center. Today, many experts recommend early, aggressive treatment to protect vulnerable joints.

Remission is increasingly possible thanks to new therapies, which can be used alone or in combination. Your doctor will work with you to develop a treatment plan that addresses your individual needs. YourRA treatmentplan may include non-steroidal anti-inflammatory drugs (NSAIDs),corticosteroids, and disease-modifying anti-rheumatic drugs (DMARDs) — a wide category of immune-suppressing drugs that includes biologics as well as the newest approved RA treatment option, janus kinase (JAK) inhibitors, according to the AF.

In addition, making healthy lifestyle choices, like gettingregular exercise, maintaining a healthy body weight, and following an anti-inflammatory diet, likethe Mediterranean diet,可以帮助你感觉更好,促进健康的joints, the AF adds. According to a study published in August 2018 in the journalArthritis Care & Research,people with RAwho were overweight were 25 percent less likely than those at a healthy weight to achieve sustained remission in the first three years followingRA diagnosis, despite being on the same treatment. Those who were obese were 74 percent less likely.

Working closely with your rheumatologist can help you find the most effective combination of lifestyle changes and medication to gain control of your RA — and your life.

Even if it takes some time to find the right treatment for you, it’s important to stick with it. Though you may find symptom relief fairly quickly, “finding the right medication for prolonged care can take longer," Pisetsky explains. "Usually, several months can elapse before it is clear if a treatment is working or not and whether it’s time to try something new.”

治疗类风湿性关节炎是一个长期的承诺,所以找到一个rheumatologist you feel comfortable with, and don’t get discouraged if a particular drug doesn’t work for you. Give your body time to respond to new medications, and let your doctor know of any concerns you may have about your treatment.

Additional reporting by Erica Patino.

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