8 Common Medications That May Cause Dehydration

Drugs for conditions including cancer, high blood pressure, and type 2 diabetes may cause a water imbalance. If you’re taking any of these meds, it's crucial to watch for signs you’re dehydrated.

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普通药物 - 这是可能的原因 - 脱水1440x810
Dehydration is a potential side effect of certain oral medications. Marc Tran/Stocksy

口渴吗?您一直在寻找副作用,例如头晕,头痛,constipation,,,,和恶心when you start a new medication, but also consider that some meds may directly or indirectly lead to dehydration.

某些药物可能会从身体中吸水,增加您的量urinate,或通过副作用造成流体损失vomiting或者腹泻,解释Aaron Emmel, PharmD,,,,the founder of PharmacyTechScholar.com in St. Augustine, Florida.

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如果您的药物将脱水列为可能的副作用,则不应停止服用该药物。与您的医生谈谈任何问题以及如何最好地处理可能的脱水。在大多数情况下,努力喝更多的水(但不要过分)将是关键。

Signs and symptoms of severe dehydration包括震颤,弱点和blurry vision,说杰西卡·努哈万迪(Jessica Nouhavandi),pharmd,位于加利福尼亚州卡尔弗市Honeybee Health的联合首席执行官和联合创始人。在极端的情况下,脱水can be fatal, so it’s always important to hydrate appropriately, pay attention to any signs andsymptoms of dehydration,,,,和alert your doctor. While it’s good to always get a complete rundown of common side effects from your pharmacist when you start a new medication, here are tips on eight drugs that have a track record of contributing to dehydration.

1.便秘的泻药

如果你有constipation,泻药可以帮助带回常规的排便(BMS)。他们指出梅奥诊所。泻药很容易获得非处方药,但您也可以得到处方泻药,例如Plecanatide(trulance),待遇irritable bowel syndrome(IBS)便秘。通过加快肠道运动,泻药会导致您的身体冲洗过多的水。“泻药刺激肠运动,并增加BMS腹泻由于流体的损失,可能导致人体脱水。” Nouhavandi博士说。这就是为什么laxative abuse很危险。她说,始终按照规定使用这些。

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2. 2型糖尿病的口服药物

如果你有2型糖尿病,您可能会服用sodium glucose co-transporter 2 (SGLT2) inhibitor,一种控制葡萄糖和血红蛋白AIC的口服片剂(HbA1C) levels and helps prevent diabetes-related complications. Options include Invokana (Canagliflozin),法xiga((dapagliflozin)和jardiance(empagliflozin), according to the约翰·霍普金斯糖尿病患者指南。SGLT2抑制剂在您的肾脏中起作用,最终导致更多的糖逃入尿液中。Mitchell Howard, PharmD,,,,a clinical assistant professor in the University of Toledo College of Pharmacy and Pharmaceutical Sciences. As a result, your kidneys will pull water from your body in order to dilute your urine, he says. This diuretic effect may have an upside: If you havehypertension,,,,your blood pressure may drop, he says, and lower your risk of心脏病

二甲双胍is another common oralmedication for type 2 diabetes;它与胃肠道不适和腹泻有关,并可能导致脱水2017年5月发表在美国老年学会杂志。在刚开始使用二甲双胍,高剂量以及以非长作用的表述的人中,这种副作用的风险尤其很高。The NHSrecommends taking small sips of water if you’re on metformin and feeling ill, and to avoid taking any medications to treat GI upset unless your doctor has okayed it.

3.偏头痛的Excedrin偏头痛

非处方偏头痛药物,Excedrin Migraine包含对乙酰氨基酚,,,,阿司匹林,,,,和咖啡因。The caffeine is designed to provide another layer of pain relief and enhances the effects of acetaminophen, according to the梅奥诊所,但它也可能产生轻度的利尿作用。Ashley Ellis,PharmD,CDCES,田纳西州科利尔维尔的Compell临床运营总监。重要的是treat migraine迅速地,由于没有理由试图忍受痛苦,但请记住,您可能想在这样做时进行水分。

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4.高血压的钾含钾和噻嗪类利尿剂

There are a few different classes of diuretics (also called “水丸”), including thiazide and potassium-sparing diuretics. Both types of diuretics are common drug高血压治疗,说the梅奥诊所。Diuretics in general trigger your kidneys to release sodium in your urine, which then takes water from your blood, helping you urinate out excess water. With less fluid in your veins, your blood pressure decreases, the medical center explains. As such, these can also contribute to dehydration. Continue to drink water normally to balance hydration levels (rather than under- or overconsuming H20).

5.心力衰竭的循环作用利尿剂

如果你有heart failure,您可能会开处方利尿剂,一种是循环利尿剂。速尿((Lasix) andbumetanide霍华德博士说,(Bumex)是两种流行的循环利尿剂。这些通过冲洗体内的累积液体的作品relieve stress在你的心中。尽管这些药物可能会导致液体损失,但这就是重点,因此您不应该自觉地喝更多的液体来弥补您可能丢失的东西。但这并不意味着您应该被烧毁。他建议:“继续喝健康的正常量,以维持水合。”因为这种药物增加了排尿霍华德补充说,在早上服用,这样您就不会整夜去洗手间。和你说话心脏病专家和初级保健医生有关如何最好地监测您的水合(临床称为流体/体积状态)。他们可能会要求您每天权衡自己,以寻找表明脱水或需要调整药物剂量的趋势。

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6.斑块牛皮癣的Apremilast

Apremilast(otezla)是一种改善中度至重度的平板电脑psoriasis通过靶向减少炎症的特定酶。最常见的副作用之一是腹泻,腹泻可能变得足够严重,可以将患者送往医院,drug manufacturer notes。In theirclinical studies,,,,17 percent of patients reported diarrhea compared with 6 percent in a placebo group. Nonetheless, diarrhea should go away in the first two weeks. Ask your doctor about what your plan should be if this side effect happens to you. And, if you have symptoms of dehydration in addition to diarrhea, talk to your doctor about the best way to rehydrate.

7. Chemotherapy Drugs for Cancer

化学疗法经常用于治疗cancer,这些药物带有许多副作用,包括恶心vomiting。“呕吐的程度,其中的一些药物cause can be substantial,” says Dr. Emmel. There are many different factors that determine if your course of treatment will lead to these side effects, including type of drug, how it’s given to you, dose, and more, says the美国癌症协会(ACS)。ACS指出,您可能会为您提供抗孕药,这将有助于控制恶心。其他策略包括保留液体日记以跟踪水合,优先考虑汤,水果和蔬菜或冰棍等水上富含水的食物,以及尝试冰片,suggests the organization

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8.双相情感障碍锂

根据National Alliance on Mental Illness (NAMI),,,,(Eskalith,Eskalith CR,Lithobid)是一种情绪稳定器,可对待躁郁症。“锂会导致排尿的增加,”艾梅尔说。如果您发现自己的渴望不满,并且比平时多喝酒,请通知您的医生。这种药物会导致糖尿病脂肪,这是一种罕见的疾病,在其中您可以小便大量的尿液。某些药物可以治疗它,但您还希望喝足够的药物以抵消这种排尿,建议National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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